곤달비추출물의 항산화와 멜라닌 생성 저해 효과

• 영문명: Effect of Antioxidation and Inhibition of Melanogenesis from Ligularia stenocephala extract
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: 노언주(Eon Joo Roh) 김윤신(Yoon Shin Kim) 김병관(Beung Gwan Kim)
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제26권 제1호, 87~92쪽, 전체 6쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2009.03.31

영문 초록

In this study, we evaluated anti-oxidation and whitening effects of Ligularia stenocephala extract for use as the cosmeceuticals. L. stenocephala was extracted by three different solvents which was n-Hexane, ethyl acetate, H₂O. The free radical (1,l-diphenyl-2-picrylhydrazyl, DPPH) scavenging activity of extract of L. stenocephala was in the order: ethyl acetate fraction of leaf (IC₅₀ value of 10.512ug/mL) 〉 ethyl acetate fraction of stem (IC₅₀ value of 31.877ug/mL) 〉 H₂O fraction of leaf (IC₅₀ value of 129.194ug/mL). Reactive oxygen species (ROS) scavenging activity of extract of L. stenocephala was in the order: ethyl acetate fraction of leaf (IC₅₀ value of 0.230mg/mL) 〉 ethyl acetate fraction of stem (IC₅₀ value of 0.528mg/mL) 〉 H₂O fraction of leaf (IC₅₀ value of 0.799mg/mL). Tyrosinase inhibition activity of L. stenocephala extracts was reduced 29.477% on ethyl acetate fraction of leaf, 13.583% on ethyl acetate fraction of stems. Therefore, L. stenocephala extracts may be useful as a new antioxidant and whitening agent to inhibit melanogenesis.

목차

Abstract

1. 서론

2. 실험

3. 결과 및 고찰

4. 결론

참고문헌

키워드

Ligularia stenocephala anti-oxidation free radical cosmeceutical