새로운 Aminopyrimidinylmethanone 유도체의 합성

• 영문명: Synthesis of New Aminopyrimidinylmethanone Derivatives
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: 안혜미(Hye Mi Ahn) 유경호(Kyung Ho Yoo)
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제26권 제1호, 60~68쪽, 전체 9쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2009.03.31

영문 초록

In this work, the synthetic approaches for a series of aminopyrimiclinylmethanone derivatives 1a-i, which versatile biological activities such as antibacterial and anticancer activities are expected from a structural point of view, were described. Nicotinic acid was converted to (2-methylsulfonylpyrimidin-4-yl) (pyridin-3-yl)methanone, a key intermediate, which was reacted with nucleophiles to yield the desired aminopyrimidinylmethanone derivatives 1a-i bearing various substituents.

목차

Abstract

1. 서론

2. 실험

3. 결과 및 고찰

4. 결론

감사의 글

참고문헌

키워드

aminopyrimidinylmethanones synthetic approaches structural Features