아미노피리딘의 디아조화 반응

• 영문명: Diazotiation of Aminopyridines
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: 정영진(Chung YeongJin)
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제21권 제3호, 246~251쪽, 전체 6쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2004.09.30

영문 초록

Diazotization of three aminopyridine such as 3-amino-2-chloropyridine, 5-amino-2-chloropyridine, and 3-aminopyridine were investigated. Preparation of pyridinediazonium tetrafluoroborates were carried out employing two different methods. Diazotization of aminopyridines with a chlorine substituent in the pyridine ring were conducted in acidic aqueous solution with sodium nitrite in 70% and 74% yields respectively. 3-Pyridinediazonium tetrafluoroborate without any ring subsituent was unstable in an aquous solution and the diazotiation of 3-aminopyridine was proceded in an anhydrous methylene chloride-etherial BF3 solution with tert-butyl nitrite in 40% yield.

키워드

diazotiation aminopyridine pyridinediazonium tetrafluoroborates