토코페롤의 대장암세포 성장, 침윤, 부착에 대한 억제 효과

• 영문명: Inhibitory Effects of Tocopherols on Growth, Invasion, and Attachment in Human Colon Cancer Cells
• 발행기관: 충북대학교 생활과학연구소
• 저자명: 송보람(Boram Song) 주지형(Jihyeung Ju)
• 간행물 정보: 『생활과학연구논총』생활과학연구논총 제17권 제2호, 89~97쪽, 전체 8쪽
• 주제분류: 자연과학 > 생활/식품과학
• 파일형태: PDF
• 발행일자: 2013.12.31

영문 초록

The aim of the study was to investigate the inhibitory effects of different forms of tocopherols (T) on cell growth, invasion, and attachment in HCT116 human colon cancer cells. Treatment with γ-T and δ-T significantly inhibited cell growth (by 58.1-97.8% at the concentrations of 50-100 μM), invasion (by 49.4-87.0% at the concentrations of 20-80 μM), and attachment (by 28.2-75.4% at the concentrations of 50-100 μM). α-T, however, did not exhibit such inhibitory activities. δ-T was more active than γ-T in inhibiting cell attachment at the effective concentrations (p<0.05). These studies demonstrated the inhibitory activities of γ-T and δ-T against cell growth, invasion and attachment in HCT116 cells. More studies are needed in order to elucidate detailed mechanisms for the inhibitory action of γ-T and δ-T.

목차

Abstract

Ⅰ. 서론

Ⅱ. 재료 및 방법

Ⅲ. 결과 및 고찰

Ⅳ. 결론 및 제언

Ⅴ. 감사의 글

참고문헌

키워드

Tocopherol Colon Cancer Cell Growth Invasion Attachment