학술논문
침전극 저주파자극이 흰쥐의 Caspase-3, 9와 Neuronal Nitric Oxide Synthase 면역반응세포 변화에 미치는 영향
이용수 14
- 영문명
- The Effect of Needle Electrode Electrical Stimulation on the Change of Caspase-3, 9 and Neuronal Nitric Oxide Synthase Immunoreactive Cells in the Sprague Dawley Rats
- 발행기관
- 한국전문물리치료학회
- 저자명
- 김수한(Kim Soo-han) 최흥식(Choi Houng-sik) 김택훈(Kim Tack-hoon) 신헌석(Cynn Heon-seock) 김지성(Kim Ji-sung) 송치원(Song Chi-won)
- 간행물 정보
- 『한국전문물리치료학회지』한국전문물리치료학회지 제11권 제2호, 47~62쪽, 전체 16쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 2004.06.30
국문 초록
영문 초록
In most tissues, apoptosis plays a pivotal role in normal development and in regulation of cell number. Therefore inappropriate apoptosis is revealed in a variety of diseases. This study was carried out to investigate the effects of acupuncture and needle electrode electrical stimulation on the change of caspase-3, 9 and neuronal nitric oxide synthase (nNOS) immunoreactive cells in the Sprague Dawley rats(SD rat). In immobilized SD rats (n=5), enhanced caspase-3 and caspase-9 expression were detected in the reticular part of substantia nigra, and enhanced nNOS was detected in the dorsolateral periaqueductal gray (DL-PAG) of midbrain and the paraventricular nucleus (PVN) of the hypothalamus using immunohistochemistry. Following the immobilization, acupuncture (n=5) and needle electrode electrical stimulation (n=5, 2 ㎐) was applied at Hégŭ (L14) acupoint of SD rats, respectively. The stress-induced enhancement in the expression of caspase-3, 9 and nNOS were The present results demonstrate that and needle electrode electrical stimulation are effective in the modulation of expression of caspase-3, 9 and nNOS induced by immobilization.
목차
Abstract
Ⅰ. 서론
Ⅱ. 연구방법
Ⅲ. 결과
Ⅳ. 고찰
Ⅴ. 결론
인용문헌
해당간행물 수록 논문
참고문헌
최근 이용한 논문
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!