Brain Activation in Response to Literature-Related Activities

• 발행기관: 대한신경정신의학회
• 저자명: Seungpil Jeong Ji Sun Hong Doug Hyun Han
• 간행물 정보: 『Psychiatry Investigation』제22권 제5호, 574~582쪽, 전체 9쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2025.05.15

국문 초록

Objective A humanities-based approach to understanding the brain can yield valuable insights, advancing neuroscience and enhancing mental, emotional, and social well-being. This study was aimed at exploring how engagement in literature-related activities stimulates brain activity in the prefrontal cortex. Methods We recruited 24 healthy male participants aged 20 to 29 years. They completed clinical scales assessing depression, anxiety, attention, and humanistic knowledge. They also performed six tasks comprising various literature-related cognitive challenges while hemodynamic changes in their frontal cortices were measured using functional near-infrared spectroscopy. Results Task 1 (word memory and recognition) increased activation in the ventrolateral prefrontal cortex (VLPFC), as did Task 2 (emotional words classification), which also elevated activity in the left orbitofrontal cortex (OFC). Task 3 (understanding context) increased activation in the dorsolateral PFC (DLPFC). Tasks 4 (interpersonal relationship) and 5 (listening, memory, understanding, and expression) drove similar increases in the frontopolar and DLPFC regions. Task 6 (creative activities using characters and items) significantly activated multiple regions, including the right and left VLPFC and OFC. Humanistic knowledge scores were positively correlated with left and right DLPFC activation in Tasks 3 and 5, respectively. Conversely, Task 6 showed negative correlations between attention-deficit/hyperactivity disorder scores and both right DLPFC and right OFC activation. Conclusion This study identified key brain regions involved in literature activities. Complex activities (semantic processing, understanding and creative expression, decision-making and emotional regulation, etc.) stimulated various regions of prefrontal cortices, including the VLPFC, DLPFC, and OFC.

목차

INTRODUCTION

METHODS

RESULTS

DISCUSSION

REFERENCES

키워드

Humanities Literature Cognition Prefrontal cortex Functional near-infrared spectroscopy