Preliminary study on change in the upper airway dimension in growing patients with Pierre-Robin sequence

• 발행기관: 대한치과교정학회
• 저자명: Su-Ji Yoon Il-Hyung Yang Su-Jung Kim Seung-Hak Baek
• 간행물 정보: 『The Korean Journal of Orthodontics』제55권 제2호, 105~119쪽, 전체 15쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2025.03.25

국문 초록

Objective: This study aimed to evaluate the changes in upper airway (UA) dimensions in growing patients with Pierre-Robin sequence (PRS). Methods: The subjects were 23 PRS patients who had not undergone growth modification therapy or surgical intervention. Their lateral cephalograms were obtained longitudinally at mean ages of 8.81 (T0) and 14.05 (T1). Patients were categorized based on their SNB value at T0 (Criteria: –2 SD): Group-1 (very retrusive mandible, n = 13) and Group-2 (moderately retrusive mandible, n = 10). Skeletal and UA variables at T0 and T1, as well as ΔT0-T1, were statistically analyzed. Results: At T0, Group-1 exhibited more retrusive maxilla and mandible (SNA, P < 0.01; SNB, P < 0.001), a more hyperdivergent pattern (facial height ratio, P < 0.05), and a more posteriorly positioned hyoid bone (H-PTV, P < 0.05), while Group-1 showed larger UA spaces (superior pharyngeal airway space [SPAS] and inferior pharyngeal airway space, all P < 0.05) than Group 2, which might indicate the existence of a compensatory response to maintain the UA patency. At T1, Group-1 maintained significantly retrusive maxilla and mandible (SNA and SNB, all P < 0.01), exhibited a less anteriorly positioned tongue (TT-PTV, P < 0.05), and displayed a more obtuse soft palate angle (SPA, P < 0.05) than Group-2. Between T0 and T1, Group-1 demonstrated significant increases in the hyoid symphysis distance (ΔH-RGN, P < 0.001), tongue length (ΔTGL, P < 0.01), and pharyngeal UA spaces (ΔSPAS and ΔPNS-ad2, all P < 0.001). Conclusions: Even in growing PRS patients with severe mandibular retrusion, the UA dimensions increased due to forward growth of the mandible, repositioning of tongue and hyoid bone, and existence of compensatory mechanism.

목차

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

CONCLUSIONS

키워드

Upper airway,Pierre-Robin sequence