항 강글리오사이드 항체 양성환자의 임상적 특징

• 영문명: Clinical Characteristics of Patients with Positive of Anti Ganglioside Antibody
• 발행기관: 조선대학교 의학연구원
• 저자명: 정지연(Ji Yeon Chung) 추인성(In Sung Choo)
• 간행물 정보: 『The Medical Journal of Chosun University』제40권 제3호, 101~107쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2015.09.30

영문 초록

Guillain-Barré syndrome can be classified with several subtypes along with the union of each symptom. Autoimmune mechanism is accepted for pathogenesis. It is often difficult to predict the causative antibodies of the various types of Guillain-Barré syndrome, because there are considerable mismatches of causative antibody to clinical phenotype as well as phenotype or antibody heterogeneities. We investigated the clinical characteristics of the patients with positivity of anti-gangliosides antibody in the serum. Nineteen patients were enrolled who showed the positivity of anti-GM1 antibody, anti-GQ1b antibody and anti-GD1b antibody, who had visited the department of neurology of Chosun University Hospital. We classified the three patient groups; 8 patients had positivity for anti-GM1 antibody, 10 patients for anti-GQ1b antibody and 8 patients for GD1b antibody. The result of statistical analysis showed no clinical difference within the groups. Therefore, prediction of causative autoantibody can be risky when we considered only the symptoms and course of disease of Guillain-Barré syndrome.

목차

서론

연구대상 및 방법

결과

고찰

키워드

Guillain-Barré syndrome Fisher syndrome Anti-gangliosides antibody