Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate

• 영문명: Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate
• 발행기관: 대한생리학회-대한약리학회
• 저자명: Jieun Ro Yeongseok Kim Hyeongmin Kim Soung Baek Jang Hyun Joo Lee Suharto Chakma Ji Hoon Jeong Jaehw
• 간행물 정보: 『The Korean Journal of Physiology & Pharmacology』제17권 제3호, 197~201쪽, 전체 5쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2013.01.01

영문 초록

The purpose of this study was to examine the anti-oxidative activity of pectin and other polysaccharides in order to develop a cosmeceutical base having anti-oxidative effects towards retinyl palmitate (RP). The anti-oxidative stabilizing effects of pectin and other polysaccharides on RP were evaluated by DPPH assay and then the stabilizing effect of pectin on RP was examined as a function of time. Among the polysaccharides we examined, pectin exhibited a considerably higher anti-oxidative activity, with an approximately 5-fold greater DPPH radical scavenging effect compared to other polysaccharides. The DPPH radical scavenging effect of pectin increased gradually with increasing concentrations of pectin. At two different RP concentrations, 0.01 and 0.1% in ethanol, addition of pectin improved the stability of RP in a concentration dependent manner. The stabilizing effect of pectin on RP was more effective for the lower concentration of RP (0.01%, v/v). Further, degradation of RP was reduced following the addition of pectin as measured over 8 hours. From the results obtained, it can be suggested that pectin may be a promising ingredient for cosmeceutical bases designed to stabilize RP or other pharmacological agents subject to degradation by oxidation.

키워드

Anti-oxidative effect Cosmeceuticals Pectin Polysaccharides Retinyl palmitate