정신분열병 고위험군에서의 뇌영상 연구

• 영문명: Neuroimaging Findings in Subjects at High Risk for Developing Schizophrenia
• 발행기관: 대한신경정신의학회
• 저자명: 최정석 권준수
• 간행물 정보: 『신경정신의학』제47권 제5호, 430~440쪽, 전체 11쪽
• 주제분류: 의약학 > 정신과학
• 파일형태: PDF
• 발행일자: 2008.09.30

영문 초록

The pathophysiology of schizophrenia may be influenced by interaction of genetic, neurodevelopmental, environmental and/ or psychological factors, which make it difficult to elucidate the etiology of the disorders through clinical phenomenology. Therefore, it needs to find out endophenotypes specific to schizophrenia before onset of clinical expressions. Recently, many researchers have been concerned about subjects at high risk for schizophrenia genetically or clinically using neuroimaging techniques. In this review, we summarized neuroimaging findings performed on subjects at high risk for schizophrenia. In genetic high risk subjects, fronto-temporal abnormalities were observed, while clinical high risk subjects showed frontal abnormalities, suggestive of susceptibility markers to schizophrenia

목차

서 론

유전적 고위험군

임상적 고위험군

결 론

REFERENCES

키워드

Schizophrenia High risk Neuroimaging