Effect of functional food containing low-molecular-weight chito oligosaccharide on mice induced to become obese by high-fat diet

• 영문명: Effect of functional food containing low-molecular-weight chito oligosaccharide on mice induced to become obese by high-fat diet
• 발행기관: 한국예방수의학회
• 저자명: Sunju So OKjin Kim Hye-Yeong Kwon Hyun-A Lee
• 간행물 정보: 『Journal of Preventive Veterinary Medicine』Vol.48, No.2, 98~104쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2024.06.30

국문 초록

Obesity occurs when the body consumes more energy than it requires and uses less energy, resulting in the accumulation of fat, which increases the number and size of fat cells in the body. It causes high blood pressure, type 2 diabetes, and joint crowding, making it difficult to fully treat. We investigated the effects of chito oligosaccharide(CHO) functional material, which suppresses fat accumulation, restores dyslipidemia values, and has no side effects.In this study, we investigated the ameliorative effects of CHO on obese mice fed a high-fat diet. The experimental groups were divided into 5 groups (n=10) of C57BL/6 mice: normal control (N), control group (C), and chito oligosaccharide low concentration (L), medium concentration (M), and high concentration (H) groups. We tested whether CHO has an effect on obesity through body weight and adipose tissue weighing, serum lipid testing, and histological examination. Experimental analysis showed that CHO reduced body weight and adipose tissue weight, improved the concentrations of TCHO, TG, HDL, and LDL, which are factors for dyslipidemia diagnosis, and decreased the diameter size of adipose tissue. These results suggest that CHO alleviates the levels of fat growth inhibition and dyslipidemia levels in obese-induced mice, and has a positive effect on obesity.

키워드

High fat diet Low-molecular-weight Chito oligosaccharide Functional Foods obesity