PET/CT 검사에서 Flow mode를 적용한 Respiratory Gating Method 촬영과 추가 Gating 촬영의 비교 및 유용성 평가

• 영문명: Comparison and Evaluation of the Effectiveness between Respiratory Gating Method Applying The Flow Mode and Additional Gated Method in PET/CT Scanning.
• 발행기관: 대한핵의학기술학회
• 저자명: 장동훈(Donghoon Jang) 김경훈(Kyunghun Kim) 이진형(Jinhyung Lee) 조현덕(Hyunduk Cho) 박소현(Sohyun Park) 박영재(Youngjae Park) 이인원(Inwon Lee)
• 간행물 정보: 『핵의학기술』Vol.21 No.1, 54~59쪽, 전체 6쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2017.06.30

영문 초록

Purpose The present study aimed at assessing the effectiveness of the respiratory gating method used in the flow mode and additional localized respiratory-gated imaging, which differs from the step and go method. Materials and Methods Respiratory gated imaging was performed in the flow mode to twenty patients with lung cancer (10 patients with stable signals and 10 patients with unstable signals), who underwent PET/CT scanning of the torso using Biograph mCT Flow PET/CT at Bundang Seoul University Hospital from June 2016 to September 2016. Additional images of the lungs were obtained by using the respiratory gating method. SUVmax, SUVmean, and Tumor Volume (cm³) of non-gating images, gating images, and additional lung gating images were found with Syngo,bia (Siemens, Germany). A paired t-test was performed with GraphPad Prism6, and changes in the width of the amplitude range were compared between the two types of gating images. Results The following results were obtained from all patients when the respiratory gating method was applied: SUVmax = 9.43 ± 3.93, SUVₘₑₐₙ = 1.77 ± 0.89, and Tumor Volume = 4.17 ± 2.41 for the non-gating images, SUVmax = 10.08 ± 4.07, SUVₘₑₐₙ = 1.75 ± 0.81, and Tumor Volume = 3.56 ± 2.11 for the gating images, and SUVmax = 10.86 ± 4.36, SUVₘₑₐₙ = 1.77 ± 0.85, Tumor Volume = 3.36 ± 1.98 for the additional lung gating images. No statistically significant difference in the values of SUVₘₑₐₙ was found between the non-gating and gating images, and between the gating and lung gating images (P>0.05). A significant difference in the values of SUVₘₐₓ and Tumor Volume were found between the aforementioned groups (P<0.05). The width of the amplitude range was smaller for lung gating images than gating images for 12 from 20 patients (3 patients with stable signals, 9 patients with unstable signals). Conclusion In PET/CT scanning using the respiratory gating method in the flow mode, any lesion movements caused by respiration were adjusted; therefore, more accurate measurements of SUVₘₐₓ, and Tumor Volume could be obtained from the gating images than the non-gating images in this study. In addition, the width of the amplitude range decreased according to the stability of respiration to a more significant degree in the additional lung gating images than the gating images. We found that gating images provide information that is more useful for diagnosis than the one provided by non-gating images. For patients with irregular signals, it may be helpful to perform localized scanning additionally if time allows.

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서론

실험재료 및 방법

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결론 및 고찰

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REFERENCES

키워드

Flow mode Respiratory Gating Method SUVₘₐₓ Tumor Volume