The Effects of 20-hydroxyecdysone in Drosophila Kc Cells on the Ecdysteroidosis

• 발행기관: 한국환경보건학회
• 저자명: Hwang, Seong-Hee Kim, Pan-Gyi
• 간행물 정보: 『한국환경보건학회지』제28권 제4호, 1~5쪽, 전체 5쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2002.11.30

영문 초록

Drosophila Kc cells are ecdysone-responsive : hormone treatment leads rapidly to increased synthesis of several ecdysone-inducible polypeptides (EIPs) and to commitment to eventual proloferative arrest. Later the treated cells undergo morphological transformation, cease to proliferate and to grow. These responses have proven useful as models for studying ecdysone action and environmental endocrine disrupting actions. In this study, we used 20-HE to check out the Kc cells properties to the ecdysone and this properties will be applied to the environmental chemicals to find out the endocrine disrupting action in ecosystem. The cell counts of cultures harvested after 3 days growth in the presence of 20-hydroxyecdysone. In Kc cell cultures, there were statistically significant different from control cells at 20HE 10/sup 7/-10/sup 5/. The morphological effects of all the hormones were similar, differing only in the dose level at which they were initiated.

목차

Introduction

Materials and Methods

Results and Discussions

References