참당귀 세미 추출물의 미백 및 항산화 효과

• 영문명: Whitening and Antioxidant Effects of Extracts from Angelica gigas Nakai Thin Root
• 발행기관: 한국자원식물학회
• 저자명: 이상훈(Sang-Hoon Lee) 박정용(Jeong-Yong Park) 서경혜(Kyung Hye Seo) 최장남(Jang Nam Choi) 이윤정(Yoon-Jeong Lee) 문윤호(Youn-Ho Moon) 허목(Mok Hur) 박우태(Woo Tae Park) 허윤찬(Yun Chan Huh) 장재기(Jae-Ki Chang) 구성철(Sung Cheol Koo)
• 간행물 정보: 『한국자원식물학회지』제34권 제1호, 37~43쪽, 전체 7쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2021.02.28

영문 초록

Angelica gigas Nakai (AGN) is a perennial plant belonging to the family Apiaceae. Its root has been utilized as a traditional medicine especially in Korea. This study was carried out to evaluate the potential use of extracts from AGN root parts as a cosmetic material. The dried AGN roots are divided into body (B), thick root (TkR), medium root(MR) and thin root (TnR) according to their diameter before cutting into medicine. B, TkR and MR of AGN are combined and used as medicinal herbs (MH). The extracts from AGN each root part (B, TkR, MR, TnR, MH) were used to test the effect on cell viability using MTS assay and to examine inhibitory effect on melanin accumulation in B16F10 melanoma cells. All extracts (50 - 200 ㎍/mL) from the each root part did not affect the cell viability. And inhibitory effect of all root extracts (200 ㎍/mL) on melanin accumulation was 12-19%. Especially, TnR showed similar inhibitory effect on melanin accumulation to MH. In addition, DPPH and ABTS free radical scavenging activity were higher in the TnR extract compared to MH. This study showed that the TnR extract exhibit high inhibitory effect on melanin accumulation and antioxidant activity compared to MH, suggesting that TnR extract has potential as a cosmetic ingredient.

목차

서 언

재료 및 방법

결과 및 고찰

키워드

Angelica gigas Nakai Antioxidant activity Melanin Thin root