모 지역의 소아 백혈병 및 악성림프종 발병 사례와 환경적 요인의 연관성 조사

• 영문명: Association of the Risk of Leukemia and Non-Hodgkin’s Lymphoma (NHL) with Environmental Agents
• 발행기관: 한국환경보건학회
• 저자명: 박동욱(Dong-Uk Park) 최상준(Sangjun Choi):윤간우(Kanwoo Youn):김소연(So-Yeon Kim):김희윤(Hee-Yun Kim):박윤경(Yun-Kyung Park):김 원(Won Kim):임상혁(Sanghyuk Iim):박지훈(Jihoon Park)
• 간행물 정보: 『한국환경보건학회지』제45권 제3호, 203~212쪽, 전체 10쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2019.06.30

영문 초록

Objective: A total of five students at same middle school were reported to be diagnosed with pediatric leukemia (n=2), non-Hodgkin’s lymphoma (NHL, n=1) and aplastic anemia (n=2) between 2016 and 2017. The aims of this study are to assess exposure to environmental hazardous agents known to be associated with the risk of leukemia and to examine whether the environment of school is associated with the risk leukemia. Method: A total of 11 environmental agents causing childhood leukemia were monitored using international certified method in schools where patients had ever attended. Radon & Thoron detector was used to monitor realtime airborne radon and thoron level (Bq/m3). Clinician interviewed two among nine patients who agreed to participate in this study in order to examine the association of demographic and genetic factors by individually. Leukemia, NHL, and aplastic anemia were grouped into lymphohematopoietic disorder (LHP). Results: Except for airborne radon level, no environmental agents in school and household where patients may be exposed were found to higher than recommended airborne level. Clinical investigation found no individual factors that may be associated with the risk of LHP. Higher airborne radon level than Korea EPA’s airborne radon criteria (148 Bq/m3) was monitored at most of several after-class room of one elementary school, where two leukemia patients graduated. Significant radon level was not monitored at class-room. Significant exposure to radon of patients was not estimated based on time-activity pattern. Conclusions: Our results have concluded that there have been no environmental factors in school and household environment that may be associated the risk of LHP.

목차

I. 서 론

II. 연구 대상 및 방법

III. 결 과

IV. 고 찰

V. 결 론

키워드

Benzene radon environmental disease environmental agents