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학술논문

Gross age-related changes and diseases in human heart valves

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영문명
발행기관
대한해부학회
저자명
Treerat Gumpangseth Pasuk Mahakkanukrauh Srijit Das
간행물 정보
『Anatomy and Cell Biology』Vol.52(1), 25~33쪽, 전체 9쪽
주제분류
의약학 > 의학일반
파일형태
PDF
발행일자
2019.03.30
4,000

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국문 초록

영문 초록

Cardiac valves are highly complex structures optimizing their function during the cardiac cycle. They open and close directed by blood flow under different pressure conditions in the dynamic environment in the heart. It is acknowledged that the aging process affects the structure and functions of the heart valves. With regard to morphometry, age-related changes of the heart valve can be found in valve circumference, thickness of the leaflet, luminal area at the sinotubular junction, valve diameter, orifice area, and leaflet size in circumferential and radial direction. In addition, there are differences between male and female hearts in some features. Moreover, there are studies the qualitative and quantitative assessment of histological compositions, echocardiography study to investigate the annular circumference and diameter in the human heart valves related with age. Studies into the detailed anatomy of the changes in heart valves with age are important and the correlation between valve morphology and age may be used as an age indicator. This study reviews the basic anatomical structure of the heart valves, age-related changes of valve morphometry, heart valve diseases, and general treatment of valvular diseases in humans. Detailed knowledge of the anatomical features of the morphology of the human heart valve is useful for any treatments of valve pathology.

목차

Introduction
Anatomy of the Heart Valves
Tricuspid Valve
Mitral Valve
Pulmonary Valve
Aortic Valve
Heart Valves Morphometry Change with Age
Diseases Affecting Heart Valves
Rheumatic Valve Disease
Endocarditis
Treatment of Heart Valves Dysfunction
Future Direction
Conclusion
References

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APA

Treerat Gumpangseth,Pasuk Mahakkanukrauh,Srijit Das. (2019).Gross age-related changes and diseases in human heart valves. Anatomy and Cell Biology, 52 (1), 25-33

MLA

Treerat Gumpangseth,Pasuk Mahakkanukrauh,Srijit Das. "Gross age-related changes and diseases in human heart valves." Anatomy and Cell Biology, 52.1(2019): 25-33

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