Anti-diabetic effect of amaranth grain ethanol extract on diabetic db/db mice

• 발행기관: 한국예방수의학회
• 저자명: Tae Woo Kim Eun Kyung Lee Byung Chan Kim Sung Rock Kim Da Jung Kim Myeong Jae Lee Min Ji Kim Nam Chi
• 간행물 정보: 『Journal of Preventive Veterinary Medicine』Vol.40, No.4, 115~119쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2016.12.30

영문 초록

This study investigated the antidiabetic effect of amaranth grain ethanol extract (AEE) in a diabetic animal model, db/db mouse. The mice were divided into 4 groups: normal control mice (C57BL/6J), diabetic mice (C57BL/6J db/db), diabetic mice fed a lower concentration of AEE (0.3 mg/kg), and diabetic mice fed a higher concentration of AEE (0.5 mg/kg). After 10 weeks of treatment, body weights, blood insulin levels and blood glucose levels of each group were compared. At the end of treatment, the results showed that both AEE supplemented groups had lower body weights than those in the diabetic groups although higher than those in the normal groups. Moreover, in both AEE supplemented groups, serum insulin levels were higher and blood glucose levels were lower than those in the diabetic groups although both values were higher than those in the normal groups. The results of this study suggest that AEE can alleviate many of the common symptoms of diabetes in diabetic mice and, therefore, has potential as a therapeutic supplement for normalization of blood glucose and insulin levels in humans.

목차

서 론

재료 및 방법

결 과

고 찰

키워드

Amaranth grain extract serum glucose serum insulin antidiabetic effect