가토 상악동 거상술 후 Bovine Bone (Bio-Oss)과 함께 이식된 혈소판풍부혈장과 혈소판결핍혈장의 골치유능 비교

• 영문명: Effect of bovine bone (Bio-Oss) and platelet rich plasma, platelet poor plasma on sinus bone graft in rabbit
• 발행기관: 대한구강악안면외과학회
• 저자명: 이태형(Tai-Hyung Lee) 정유민(You-Min Jeong) 최용근(Yong-Kun Choi) 이의석(Eui-Seok Lee) 장현석(Hyon-Seok Jang) 임재석(Jae-Suk Rim)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면회과학회지 제36권 제1호, 39~42쪽, 전체 4쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2010.02.28

영문 초록

Maxillary sinus lift and bone graft are used to reconstruct atrophic maxilla molar area for endosseous dental implants. Many different grafting materials and techniques can be used for maxillary sinus bone graft. Bio-Oss has been proposed as bone substitute and successfully utilized as osteoconductive filler. Platelet rich plasma (PRP) is an autologous material with many growth factors, such as PDGF, TGF-β, IGF, VEGF, facilitating bone healing process. And Platelet poor plasma (PPP) is the by-product in procedure of producing PRP. Six rabbits were used as experimental animal. Both maxillary sinus were grafted with Bio-Oss􀋓 and PRP, and Bio-Oss and PPP. Rabbits were sacrificed at 4, 8 and 12 weeks. The grafting sites were evaluated by histomorphometric analysis. As a result, using PRP showed excellent bone formation in the early stage, but no further significant effect after that. In late stage, the ability of bone formation of using PRP was even worse than using PPP. The further studies need to be considered in this case.

키워드

Maxillary sinus Bio-Oss Platelet-rich plasma (PRP) Platelet poor plasma (PPP)