학술논문
Method Development for the Profiling Analysis of Endogenous Metabolites by Accurate-Mass Quadrupole Time-of-Flight(Q-TOF) LC/MS
이용수 5
- 영문명
- 발행기관
- 대한약학회
- 저자명
- LEE Insun KIM Jinho SHIM Sun Bo LEE Ji Hyun PARK Hye Jin LEE Jin Hee HWANG In Sun KIM Sungil CHO Sooyeul LEE Jung Hee CHO Su Yeon CHOI Donwoong CHO Yang Ha
- 간행물 정보
- 『춘계총회 및 학술대회』(2010년), 223~223쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2010.04.16
무료
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- A Novel Solid Self-microemulsifying Drug Delivery System (SMEDDS) Prepared by Spray-drying to Enhance the Solubility of Tacrolimus
- Biological Activities of Carotenoids and Carotenoid Extract from Carrots and Transgenic Carrots Overproducing Various Carotenoids
- Effect of Forsythiae Fructus and Its Main Component, Arctigenin, on Microglial Activation in LPS-stimulated BV-2 Cells
- Transplantation of Skeletal Myoblast Containing Genes Related to Differentiation and Angiogenesis Improves Cardiac Function in Ischemic Rat Heart Failure
- Evaluation of Anti-pigmentary Effect of Synthetic Sulfonylamino Chalcone
- An Efficient Total Synthesis of Valienamine via CSImediated Stereoselective Amination
- The Preliminary Study of Docetaxel Formulation for Intravenous Delivery with Docetaxel Prodrug
- Inhibitory Effect of Embelin, a Specific XIAP Inhibitor on the Growth of Human Prostate Cancer Cells
- Kalopanaxsaponins Isolated from Kalopanax pictus Ameliorate Memory Deficits in Mice.
- Inhibitory Effects of Captopril on Catecholamine Secretion from the Rat Adrenal Gland
- Rheology Evaluation of Natural Products for Patients with Dermatitis
- Homoisoflavonoid Derivatives from the Roots of Ophiopogon japonicus and Their In vitro Anti-inflammation Activity
- Physical Stability of Protein Drugs and Their Thermodynamic Evaluation
- Preparative Isolation of Idescarpin from the Fruit of Idesia polycarpa by High-Speed Countercurrent Chromatography
- Preparation and Evaluation of Gastic Mucoadhesive Formulations for the Improvement of Gastroprotective Effect
- Inhibitory Activity of the Root Extract from Glycyrrhiza uralensis on acyl-CoA: Cholesterol Acyltransferase (ACAT)
- Invetigation of Natural Products from Marine Resources
- Postmortem Distribution of Cyanide in 21 Victims of Cyanide Poisoning: Comparison of cYanide Concentration in Heart Blood, Peripheral Blood and Gastric Contents
- KM212 Inhibits Rat Vascular Smooth Muscle Cell Proliferation and Migration In Vitro and Improves Neointima Formation after Balloon Injury In Vivo
- Method Development for the Profiling Analysis of Endogenous Metabolites by Accurate-Mass Quadrupole Time-of-Flight(Q-TOF) LC/MS
- Burden of Disease due to COPD
- Search for Neuroprotective Substances Regulating Cytotoxicity Induced by Glutamate and Oxidative Stress
- Interleukin-6 Gene Deficiency Potentiates Age-Dependent Cognitive Impairments In Mice
- Bioavailability and Toxicokinetics of Citrate Coated Silver Nanoparticles in Rats
- Effects of Herbimycin-A on the Metabolism of Amyloid Precursor Protein
- Nitric Oxide Production Effect of an Herbal
- Anti-fatigue Effects of the Fermented GOG
- Molecular Docking Studies of Phlorotannins from Ecklonia stolonifera with BACE1 Inhibitory Activity
- Isolation and Quantitative Analysis of Peroxynitrite Scavengers from Artemisia princeps var. orientalis
- Effect of PLX-SA, a Composition of Herb Extracts, on Atopic Dermatitis in BALB/c and NC/Nga Mice
- Neuroprotective Effect of Persimmon Peel Extracts in Neuronal Cells
- Structure of New Phenylpropanoid Ester from the Rhizomes of Zingiber officinale
- Metabolomic Application to the Discrimination of Scrophularia spp. According to the Geographic Origin
- Inhibition of DNA Topoisomerases I and II and Cytotoxicity of Ulmus davidiana var. japonica
- Simultaneous Quantitation of Biomarkers for the Herbal Medicine, Polygoni Multiflori Radix by High Performance Liquid Chromatography
- The Effects of Honeybee Venom in Human Skin Wound Healing In Vitro
- Discrimination of Artemisia asiatica According to Geographic Origin with Near-Infrared Spectroscopy (NIRS) Combined with Multivariate Analysis
- In Vitro Effects of Butanol Extract of Arctium lappa L. on Anti-allergic Inflammation
- Antifibrotic Compounds from Liriodendron tulipifera Leaves and Twigs
- Quantitative Analysis of Dioscin from African Dioscorea species
- Determination of Lamivudine in Human Plasma by Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic Study
- Determination of a Peroxisome Proliferatoractivated Receptor γ Agonist, KR-62980 in Rat Plasma by Liquid Chromatography-tandem Mass Spectrometry
- A Rapid and Sensitive Determination of Rosuvastatin in Human Plasma by Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic Study
- Preparation and Characterization of a Human Serum Albumin-attached Exendin-4 derivative with Extended Hypoglycemia
- An Analytical Method of Bioactive Marker Components from Dipsaci Radix
- Comparison between Charged Aerosol Detection (CAD) and Evaporative Light Scattering Detection (ELSD) for the Analysis of Triterpenoid Saponins from Pulsatilla Koreana
- Simultaneous Determination of Glimepiride and Metformin in Human Plasma by Liquid Chromatography/Tandem Mass Spectrometry with Electrospray Ionization
- Antioxidant and Anti-diabetes Activities of Diarylheptanoid Isolated from Alnus hirsuta
- Preparation and Characterization of PEGylated TRAIL Loaded PLGA Microsphere for Dual Long Acting Effect
- Development of Novel Sodium Fusidate-loaded Wound Dressing with Polyvinyl Alcohol and Sodium Carboxymethylcellulose
- Preparation of Sustained-Release Tablet with Cilnidipine inclusion complex
- Effects of Solid Carriers on the Solubility and Oral Bioavailability Enhancement of Flurbiprofen Solid -SEDDS
- Formulation Strategies for Improving Solubility of Paclitaxel Using Surface-Modified Solid Lipid Nanoparticles with Cyclodextrin
- New Alkaloids Isolated from a Solitary Tunicate
- Decursin Inhibits Vasculogenesis in Tumorigenesis by Suppression of Endothelial Progenitor Cell Differentiation and Function
- Chemical Constituents of Chrysanthemum zawadskii var. latilobum
- A New Anti-allergenic Sesquiterpene from the Rhisomes of Cyperus rotundus
- Drug-Interaction Study of Phenolsulfonphthalein with Propylenglycol
- Solubilization of Amphotericin B by Inclusion Complex and pH-Sensitive Degradation Using Multiblock Copolymer Gel Formulation
- Comparative Evaluations of Drug Use for Outpatients Prescribed by General Practitioner or Specialized Practitioner in ENT Area
- Cost-Effectiveness Analysis of Erlotinib versus Docetaxel as a Second or Third Line Treatment of Non Small Cell Lung Cancer in Korea
- Pharmacokinetics of Itraconazole in Diabetic Rats
- Evaluation of Drug Use Causing Delirium and Drowsiness in Elderly Patients of Korean
- Development of Therapeutic Duplication Criteria for Computerized Drug Utilization Review Screening
- Concurrent Drug Utilization Review: US Perspective
- Budget Impact Analysis of Oral Antiviral Agents for the Treatment of Chronic Hepatitis B in South Korea
- Models of Centralized and Joint Institutional Review Boards for Multicenter Clinical Trials
- Glyceollins Inhibits Angiogenesis and Tumor Growth by Decreasing Hypoxia-inducible Factor-1α
- The Improvement Effects on Memory and Learning by Soyasaponin B from Glycine max
- Isolation and Identification of Chemical Constituents from Leonurus japonicus
- The Anti-oxidative and Anti-inflammatory Activity Effects of Phenolic Compound from the Barks of Quercus gilva Blume
- Antifibrotic Activity of Chemical Constituents from Betula platyphylla Barks on Hepatic Stellate cells
- Phytochemical Constituents of Cynanchum paniculatum
- New Iridoids and Phenylpropanoids from Aerial Parts of Caryopteris incana (Thunb.) MIq.
- Phytochmical Constituents of the Rhizomes of Anemarrhena asphodeloides
- Biologically Active Compounds from An Endozoic Fungus Associated with the Giant Jellyfish Nemopilema nomurai
- GSK-3b-Nrf2 Signaling Pathway for Neuroprotection in Alzheimer’s Disease
- A Triterpenoid Limonoid, Obacunone Isolated from Phellodonri Cortex Exerts Anti-inflammatory Activities through NF-kB DNA Binding Inhibition in LPS-stimulated RAW264.7 Macrophages
- Anticancer Activity of Kochiae fructus in HT-29 Human Colon Cancer Cells
- Glycyrol Induces Apoptosis on Human Jurkat T Cell Leukemia through Fas-FasL/Caspase-8 Pathway
- Chemical Constituents of Betula platyphylla and Their Inhibitory Activity on Lipopolysaccharide-Induced Nitric Oxide Production in BV2 Microglia
- Dammarane-type Glycosides from Gynostemma pentaphyllum and Their Effects on IL-4-induced Eotaxin Expressionin Human Bronchial Epithelial Cells
- Antioxidative Activities of Compounds from Artemisia annua L.
- Neuroprotective Effects of Active Compounds in Triticum aestivum L. against β-Amyloid-induced Oxidative Cell Death and Scopolamine-caused Memory Impairments
- Validated LC-MS/MS Method for Simultaneous Quantification of Telmisartan in Human Plasma
- Inhibitory Effects of Inducible Nitric Oxide Synthase (iNOS) mRNA Expression and Nitric Oxide(NO) Production by Myrrh Oil
- Classification of Rhei Rhizoma using Partial Least Squares Discriminant Analysis of Bioactive Components by HPLC
- A Rapid and Sensitive Determination of Olmesartan Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic Study
- Screening of Small Molecules to Discover a Potent Inhibitor of ESX-Sur2 Interaction
- Effects of Myricetin, an Antioxidant, CYP2C9, 2D6 and P-gp Inhibitor in vitro, on the Pharmacokinetics of Carvedilol in Rats
- The Establishment of Analytical Method of New Restricted Preservatives in Cosmetics
- Chiral Separation of Decursinol Angelate and Decursin Derivatives on OD-H Column by HPLC
- Exendin-4 Derivative Conjugated with Palmitylamine Modified-PEG as an Injection-Based Long-Acting Anti-Diabetic Treatment
- In-line Monitoring of the Polymorphic Transformation via NIRS
- Determination of Stability Constants for Fluvastatin Enantiomer and Hydroxypropyl-β-cyclodextrin Complex
- Preparation of Nadolol Enantiomers using (-)-MCF as a Chiral Derivatizing Reagent
- Structural Analysis of Tumor Suppressor TGF-β Stimulated Clone 22 (TSC-22)
- Effects of Process Parameters on the Emulsion Droplet Size and Distribution Using SPG Membrane Emulsification
- Development and Validation of Dissolution Tests for Trimetazidine Hydrochloride Tablets in Korea Pharamceutical Codex
- Niacinamide as a Crystal Growth Inhibitor for the Preparation of Megestrol Acetate Nanopowder by Liquid Precipitation and Spray Drying
- Effect of Chemical Conjugation on Inhibiting Peptide Acylation in PLGA Matrix
- A New Method to Prepare Nanosuspensions for Ocular Delivery
- Pharmacokinetic Study of Rosiglitazone in Diabetes Animal Model
- Method Validation of Everted Gut Sac Technique for Glucose Intestinal Absorption
- Improved Dissolution of Biochanin A, a Bioflavonoid, via the Preparation of Solid Dispersion
- Enhanced Solubility and Oral Bioavailability of Silymarin by Using Membrane Emulsification Technique
- Physical Property Modification of Glimepiride Using Various Recrystallization Processes
- Conformational Changes in Escherichia coli Tryptophan Synthase β2 Subunit
- Effects of Silybinin, an Antioxidant, on the Pharmacokinetics of Losartan in Rat.
- Physicochemical Characterization of Tacrolimus Sustained-release Tablet Prepared by Solubility-enhanced Solid Dispersion System
- Preparation of Porous Poly(lactic-co-glycolic acid) Microspheres by pH Control Using Gelatin Porogen
- 2009 Summarized Report of ADME/Tox Screening Data in KRICT
- Apigenin, an Antioxidant, Enhanced the Bioavailability of Etoposide in Rats
- Pharmacokinetic Characteristics of Lornoxicam in relation to CYP2C9*3 Allele in Healthy Korean Subjects
- The Necessity of Vaccine Education for Pharmacists and Development of a Vaccine Leaflet for Patient Counseling
- The Pharmacy Health Promotion Program in Major Countries
- Review of Implementation of Prescribing Incentive Scheme in UK
- Study to Improve Medicine Approval System through Comparisons with Major Advanced Countries
- Modeling the Arrhythmogenic Property of Levofloxacin in Guinea-pig
- Study of the Guideline for Clinical Evaluation of Gastroenterology Drug
- Preparation and Characterization of Gemcitabine Micro/nanoparticles for Oral Delivery
- Anti-obesity Effect and Action Mechanism of Cinnamaldehyde in High Fat Diet Induced Mice
- New Small Molecules Targeting Hypoxia-inducing Factor-1 Signaling and Angiogenesis
- Antitubercular Nitroimidazoles : Aerobic and Anaerobic Activities
- Challenges and Opportunities in Biosimilars
- Analysis of Coding of Fear Memory in the Amygdale with Temporal and Cellular Resolution
- Novel DGAT Inhibitors as Potential Anti-Obesity Agents
- Design and Synthesis of Small Molecule Ligands for Oncogenic Ras Proteins
- Development of Long-Circulating Pegylated Granulocyte Colony Stimulating Factor
- Neurovascular and Neurodegenerative Diseases of Retina
- Educational Significance of PBL, and the Management of PBL in Medical School
- Role of the Extended Aamygdala in Pain-Induced Aversion
- Agonist-Induced Endocytosis and Receptor Phosphorylation Mediate Resensitization of Dopamine D2 Receptors
- Neuropsychopharmacological Potentials Modulated by Dextromethorphan Analogs
- Capillary Separation Techniques of Protein Drugs
- Development of DA-7218, a Next-Generation Oxazolidinone
- Glycan Microarrays for Functional Glycomics
- Hit to Lead Studies Based on Natural Product Prototypes
- Neuroprotective Effects of the Herbal Ethanol Extracts in 6-hydroxydopamine-lesioned Rat Model of Parkinson's Disease
- Effect of Sibutramine HCl on Cardiac hERG K+ Cannel
- Role of Ceruloplasmin in the Kainate-Induced Excitotoxicity
- Comparison of Antiangiogenic Activities of Ethanol Extracts Prepared from Several Natural Products of Plant Origin
- Role of Klotho Gene in the Cognitive Impairment
- The Beneficial Effects of Telmisartan Combined with Lacidipine on Hypertension and Other Risk Factors for Cardiovascular Disease
- Protective Effects of Neohesperidin and Poncirin Isolated from the Fruits of Poncirus trifoliata on Potential Gastric Disease.
- MeOH Extract of Hura crepitans L. Inhibits LPSInduced Inflammatory Response via Blocking of NF-kB Activation in Macrophages.
- Melittin, a Peptide Isolated from Bee Venom Toxin, Prevents Prostate Cancer Cell Growth through Modulation of NF-κB/caspase Pathway
- Anti-allergic Effect of Essential Oil from Thujopsis dolobrata by Decreasing Beta-hexoaminidase from Allergen induced RBL-2H3 Cells
- Effect of Plant-Derived Activators for AMP-Activated Protein Kinase Signaling in Metabolic Disease Animal Models
- CWP231A, First-in-Class Wnt Signaling Inhibitor for Cancer
- Lentiviral Mediated Stable Knockdown of Nrf2 Sensitizes ErbB2 Overexpressing Ovarian Cancer Cell Towards Docetaxel
- Simultaneous Analysis of Bioactive Metabolites from Rehmannia glutinosa by HPLC-DAD-MS/MS
- Drug Development with Korea Chemical Bank
- Synthesis of Anti-inflammatory Aurone Derivatives
- Norcarotenoid Glycosides from the Roots of Rehmannia glutinosa
- Solution Structure and Sequence Specificity of a Nucleic Acid Binding Protein CUGBP1ab
- Determination of Azelastine in Human Plasma by Liquid Chromatography-electrospray Tandem Mass Spectrometry (LC/ESI/MS/MS) and its Application to a Pharmacokinetic study
- Effects of Acute Renal Failure Induced by Uranyl Nitrate on the Pharmacokinetics of Liquiritigenin and Its Two Glucuronides, M1 and M2, in Rats
- Discrimination of Genotoxic and Nongenotoxic Carcinogens by Analyzing Microarray Gene Expression Data
- Triolein Emulsion Increases Vascular Permeability Transiently
- Research to Find New Bioactive Compounds from Indonesian Plants
- CDKs and Neuronal Death in Stroke
- What's New in the Drug Regulatory System : Incrementally Modified Drugs ?
- Thermodynamic Equilibration in Pd(0)-catalyzed Interconversion of Highly Constrained [2.1.2] Bicyclic Lactones: Its Mechanistic Investigation
- Structural requirements of Novel Chromone Analogs for their Inhibitory Activity Against Interleukin-5
- HS-104, a Novel Phosphatidylinositol 3-Kinase Inhibitor, Eicits Anticancer Activities in Human Liver Cancer Cells.
- Analytical Methods for Determining Effective Ingredients of Hair Nourisher Products
- Differential Effect of Genetic Variants of NTCP and OATP1B1 on the Uptake of HMG-CoA Reductase Inhibitors
- Development of a Micellar Electrokinetic Chromatography Method for the Determination of the L-enantiomer of Nateglinide
- Propenone Derivatives Inhibit Inflammatory Process In Vitro and In Vivo
- Genotoxic Effects of Silver Nanoparticles Using Bacterial System and Mammalian Cell System
- Inhibitory Effect of IL-32γ on the Growth of Colon Cancer Cell through Inhibition of NF-κB and STAT3 Signals
- Pathological Role of Pin1 in the Intimal Hyperplasia
- Study of Action Mechanism of IN-2001, a HDAC Inhibitor for the Breast Cancer Metastasis
- Alteration of Sulfur Amino Acid Metabolism between Human Breast Cancer Cells and Adriamycin Resistant Breast Cancer Cells
- Plasma Homocysteine Levels are Increased in C57BL/6 Mice Fed with High Fat Diet
- Lindera obtusiloba BL. 70% EtOH Extract Induced ERK Activation Inhibits Melanin Synthesis in Mouse B16F10 Melanoma Cells
- Antioxidation and Detoxification Potential of Wheat (Triticum aestivum) Sprout Juice in Korean Women
- Genotoxicity and Cytotoxicity of Titanium Dioxide Nanoparticles under UVA in Peripheral Blood Lymphocytes
- Selective Inhibition of Activated Stellate Cells and Protection from Carbon Tetrachloride-induced Liver Injury in Rat by a New PPARγ Agonist KR62776
- Bisphenol A Impairs Hippocampal Neurogenesis in Young Mice
- 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Induced Synaptic Disruption in Differentiated SH-SY5Y Cells
- Possible Role of the PI3kinase on the Mx1 Protein Translation and Antiviral Activity of Interferon-omegastimulated HeLa Cells
- Regulation of Autophagic and Apoptotic Cell Death by Novel Autophagy Regulators, Oxi Gene Family, in Dopaminergic Neurons
- Lycopene Inhibits Proliferation, Invasion and Migration of Human Breast Cancer Cells
- Propyl Gallate Induces Apoptosis and Cell Cycle Arrest in Activated Rat Hepatic Stellate Cells
- CoMFA on the Antiproliferative Activity of NSubstituted 2-Amino-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole Analogues against Bladder and Rectal Cancer
- Torilin from Torilis japonica Inhibiting Melanogenesis through the Down-Regulation ofMITF by Increasing ERK Activity in B16 Melanoma Cells.
- Establisment of Rapid Sterility Test for Cell Theraphy Products
- A Novel Extracellular Lipase of Streptomyces sp. CS326 Strain Newly Isolated from Korean Soil
- Purification and Characterization of a Fibrinolytic Enzyme from a Newly Isolated Streptomyces Strain
- Akt inhibitors, Alkylphospholipids, Induce Cell Death of HIV-1 Infected Macrophages
- The Antiosteoporotic Activity of Peptides in Bombycis Corpus
- Characterization and Application of a Lipase Produced by a Soil Acinomycetes
- Enzyme Activities of Bacteria Isolated from Human Feces
- Integrating Natural Products and Chemical Biology to Discover Drug Leads from Marine Cyanobacteria
- Novel Gastroretentive Drug Delivery System
- 5,5'-Substituted Indirubin-3'-oxime Derivatives as Potent Cyclin-Dependent Kinase Inhibitors with Anti-Cancer Activity
- Guideline on the Common Technical Document for NDA
- Directions for Establishment and Revision on Pharmaceutical Safety Standards
- Points to Consider in Review and Approval of New Pandemic Vaccines
- The Inflammasome and Therapeutic Interventions in the Sepsis
- Reproductive and Developmental Toxicity of Dioxin through Damage on Fetal Gonadotropins
- Constitutive Expression and Chemical-mediated Induction of Hepatic Cytochrome P450 1A (CYP1A) Subfamily Enzymes
- Bacteria-Derived Extracellular Vesicles as Vaccines for the Prevention of Nosocomial Infections
- Natural Therapeutic Magnesium Lithospermate B Potently Protects the Endothelium from Dysfunction in Diabetes
- The Effect of Selective Estrogen Receptor Modulators on the Breast Cancer Cells, MCF-7 cells and Tamoxifen-Resistant Cells
- Neuroprotective Effects of the n-Hexane Fraction from Laurus nobilis Leaves in Dopamine-Induced Cells and Animal Models of Parkinson’s Disease
- Mutation of Presenilin 2 Is Associated with Decreased Lung Tumorigenesis through Inactivation of Notch 2 Signaling
- Inhibitory Effects of PES0409 on PDGF-BB-induced Proliferation of VSMCs through Blocking PDGF-Rb Phosphorylation
- Anti-gastritic Effect and Anti-oxidant Activities of Chenopodium album Linne Extract and Fractions
- Epithelial-mesenchymal Transition in Tamoxifenresistant Breast Cancer Cells
- Therapeutic Effect of Korean Red Ginseng against Noise-Induced Hearing Loss in Animal Model
- Protection of Trimethyltin Neurotoxicity by Interleukin-6Gene
- Inhibition of SREBP-1c-mediated Hepatic Steatosis and Oxidative Stress by Sauchinone, an AMPK-activating Lignan in Saururus chinensis
- SNP1223 Inhibits Hydrogen Peroxide-Induced Apoptosis in SH-SY5Y Cells
- Exposure to Methylphenidate Alters Place Preference and Self-administration in Rats: Strain-specific Responses in Both Parameters
- Inhibitory Activities of Some Selected Antioxidant Compounds on the Chick Chorioallantoic Membrane (CAM) Angiogenesis
- Alterations in Intestinal Bacteria Metabolism Affect the Pharmacokinetic Property of Hesperidin
- Role of NRF2 Signaling in Tumor Angiogenesis of Colon Cancer Cells
- Role of the NRF2 System in TGFβ1-induced Epithelial-mesenchymal Transition in Rat Renal Epithelial Cells
- The Study of Radiosensitization of Tumor by Natural Small Molecules
- The Evaluation Methods of Anti-platelet Agents, and the Assessment of Trifusal on Anti-Platelet Aggregation Activity in Human Volunteers
- Neurotoxic Effects of Berberine in 6-Hydroxydopamine-Lesioned Rats Treated with Chronic L-DOPA
- Anti-Breast Cancer Effects of Propolis on ERPositive and ER-Negative Breast Xenograft Model
- Anti-inflammatory Activity of Methanol Extract of Elaeocarpus petiolatus (Jack) Wall. in Raw264.7 Macrophages
- The Protective Mechanism of QGC on Indomethacin-Induced Gastric Damage in Rats
- SPA019, a Natural Compound Reverses Alcoholic Fatty Liver by Inhibiting the Liver X Receptor alpha Mediated Sterol Regulatory Element Binding Protein-1c Regulatory Pathway
- Metabolomic Analysis of S-Containing Substances in Mouse Liver Treated with Silymarin Acutely
- Mechanism of Nephrotoxicity and Renal Stone Formation in Sprague-Dawley Rats Treated with Melamine and Cyanuric Acid
- A Novel Epoxypropoxy Flavonol Derivative Topoisomerases II Inhibitor, MHY-336, Induces Apoptosis in Prostate Cancer Cell
- The Carcinogenicity Evaluation of Herbal Medicines
- Reproductive Ototoxicity of TBBPA in Rat Offsprings
- Effects of Medicinal Herbs and Their Components on the Steatogenic Hepatotoxicity
- Immunomodulating Effects of Chaga Mushroom (Inonotus obliquus) in OVA-Sensitized Balb/c Mice
- Immunotoxicity Assessment of Common Traditional Korean Medicines
- Lipolysis Effects of Lancemaside A and Aglycon from Codonopsis lanceolata Water Extract in Primary Cultured Adipocytes from Obese Rat fed High Calorie High Fat Diet
- Effect and Mechanism of Morus bombycis Koidzumi on Collagen-induced Arthritis in Mice
- Determination of Some Preservatives in Distributed Cosmetics in Seoul Area
- Atrial Local Ca2+ Signaling and Inositol 1,4,5-Trisphosphate Receptors
- Effects of the Anthocyanin Isolated from the Purple-Fleshed Sweet Potato on Dimethylnitrosamine-Induced Liver Fibrosis and PDGF-BB-Dependent Signaling Pathways in Hepatic Stellate Cells
- Chemopreventive Effects of Baicalein on Dextran Sulfate Sodium (DSS)-induced Mouse Colitis
- 4-(6-Hydroxy-2-naphthyl)-1,3-bezendiol: A Potent, New Tyrosinase Inhibitor
- Cloning and Expression in Pichia pastoris of a New Cytochrome P450 Gene from a Dandruff-Causing Malassezia globosa
- Smurf2-Mediated Runx2 Degradation Is Regulated by AKT during Osteogenesis
- Autoacetylation of Human Arrest Defective 1 is Required for Tumor Growth
- Interactions of Tricyclic Isoxazoles with α2c-Adrenoceptor by Homology Modeling
- The Alpha-Helical Tip Region of MacA is Important in the Assembly of TolC in the MacAB-TolC Pump.
- Inhibitory Effect of Chalcone Derivative (JSH 03-1-10) on Lipopolysaccharide-Induced NF-kB Activation and iNOS Expression in Macrophages
- High Fat Diet Impairs Adult Hippocampal Neurogenesis: Involvement of Lipid Peroxidation and Brainderived Neurotrophic Factor
- Antioxidative and Antiinflammatory Effects of Cabbage Extracts
- Wip1 Directly Dephosphorylates Gamma-H2AX and Attenuates the DNA Damage Response
- Predicting Idopathic Toxicity of the Anticancer Agent Cisplatin with a Pharmacometabolomic Approach
- TAZ as a Novel Enhancer of MyoD-mediated Myogenic Differentiation
- Oral Administration of 2-Docosahexaenoyl Lysophosphatidylcholine Displayed Anti-Inflammatory Effects on Zymosan A-induced Peritonitis
- Bacterial Reverse Mutation Test of Bidens pilosa
- Biochemical Activities of Feline Foamy Virus Integrase Protein
- RtxA1, a RTX Toxin of Vibrio vulnificus Causes a Programmed Necrotic Cell Death through VDAC-Mediated Mitochondrial Dysfunction.
- Inhibitory Effect of In Vitro Cultured NK Cells on the Growth of Breast Cancer
- Effects of Klebsiella pneumoniae and Bifidobacterium adolescentis in TNBS-induced Colitis Mice
- A New DNA Building Block, 4'-Selenothymidine: Synthesis and Its Modification to 4'-Seleno-AZT as a Potential Anti-HIV Agent
- Synthesis of L-2’-Methylnucleoside Derivatives as Potential Anti-HCV Agent
- Cordycepin Inhibits Diabetes Relating Genes through Suppression of Inflammatory Cytokines
- Anti-inflammatory Activity of New Compounds KNU00146 by STAT-1/JAK2-mediated Inflammatory Responses Inhibition in LPS-activated Macrophages
- Growth Promoting Role of Pharma in Future Healthcare Business
- Broccoli Extract and Antioxidation
- Acai Berry(Euterpe oleracea) Inhibits Melanogenesis in B16F10 Cells
- Preparation and Characterization of PEG-heparinbased Nanoparticles with Improved Stability for the TRAIL Delivery
- Interleukin-33 Stimulates Formation of Functional Osteoclasts from Human CD14+ Monocytes
- Tanshinone IIA Enhances BMP-2-Stimulated Commitment of C2C12 Cells into Osteoblasts via p38 Activation
- Protein Kinase C-δ Regulates the Stability of Hypoxia-Inducible Factor-1α under Hypoxia
- Novel Cinchona-Aminobenzimidazole Bifunctional Organocatalysts
- Migration Order of Sibutramine Enantiomers in Capillary Electrophoresis
- Regulatory Issues in Developing of Biosimilars
- Analytical Pathways For Biosimilar Development
- Synthesis and Antitumor Activity of seco-Duocarmycin Analogs
- Resveratrol and It's Analogue, HS-1793, Inhibit Hypoxia-inducible Factor-1α and VEGF Expressions in Human Hepatocellular Carcinoma Cells
- Interleukin-11-modified Liposomes for Cancertargeted Delivery
- Monitoring of Some Bioactive Components of Lonicerae Forium et Caulis Samples Collected from Korea and China
- A New Sesquiterpenoid from Angelica koreana
- Analytical HPLC-MS/MS Method for the Determination of Pramipexole in Human Plasma and Its Application to a Pharmacokinetic Study
- Akt-targeted Immunosuppressive Effect of HQ and Its Derivatives
- Synthesis and Docking Study of 12-Oxobenzo[c]phenanthridinones and C4-Substituted 3-Arylisoquinolines as Topoisomerase 1 Inhibitors
- Ajoene, a Stable Garlic Byproduct, Has an Antioxidant Effect in Hepatocytes through Nrf2-Mediated GCL Induction
- Phenylthioureas are the Inhibitors of Melanogenesis in Melanoma B16 Cells
- Design of D-ring removed Estradiol Analogues as SERMs
- Cliona Celata Extract Inhibits Lipopolysaccharide-Induced NO Production and iNOS Expression Require Inhibition of NF-κB Activation in Murine Macrophage RAW264.7 Cells
- Preparation and Characterization of Human Serum Albumin Nanoparticles Conjugated with TNF-related Apoptosis Inducing Ligand (TRAIL)
- Physicochemical Characterizations and Pharmacokinetic Studies of Two Isoflavone Extracts
- Synthesis and Structural Optimization of Multiple H-Bonding Region of Diarylalkyl (Thio)amides as Novel TRPV1 Antagonists
- Biological Evaluation of Isoegomaketone Isolated from Perilla frutescens and its Synthetic Derivatives as Antiinflammatory Agents
- Design and Synthesis of 2,3-Dihydrobenzofuran-2-carboxylic Acid N-(Substituted)phenylamide Derivatives as NF-κB Inhibitors
- Synthesis of Novel Cinnamoylsalicylamide Analogues and their Inhibitory Activity of Wnt/β-catenin Signaling Pathway
- New Secondary Metabolites Production by Microbial Co-Culture
- Anti-Tumorigenic Activity of Sophoflavescenol against Lewis Lung Carcinoma In Vitro and In Vivo
- Effect of UG0712 on Forced Swimming Capacity in Mice
- Enrichment of Sphingosine-1-phosphate using Immobilized Metal Affinity Chromatography-Mass Spectrometry techniques in Biological Samples
- Analysis of Impurities in Methamphetamine Crystals Seized in Korea by Combination of Liquid-Liquid Extraction (LLE) and Automated Headspace Solid-Phase MicroExtraction (HS-SPME) Method
- Microchip Electrophoresis for Monitoring PEGylation of Proteins
- Effects of Specific Bifidobacterium Strains Isolated from Korean Healthy Adults on the Growth Responses of Staphylococcus aureus
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