Novel bis-ortho-Alkoxy-para-piperazinesubstituted-2,4-dianilinopyrimidines (KRCA-0008) asPotent and Selective ALK Inhibitors for Anticancer Treatment
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- 영문명
- 발행기관
- 대한약학회
- 저자명
- LEE Hyeon Ji YUN Jeong In MUHAMMAD Latif YANG Eun Hye PARK Chi Hoon KWON So Yeong CHAE Chong Hak CHOI Sang Un YUN Chang soo KIM Pilho JUNG Hee jung CHO Sung Yun KIM Hyoung Rae LEE Kwang Ho
- 간행물 정보
- 『추계총회 및 학술대회』(2013년), 477~477쪽, 전체 1쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 2013.10.18
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- Anticonvulsant Effect of Gastrodia Rhizome Processed at Different Steaming Times with Antioxidant and Anti-inflammatory Activity
- Simultaneous Determination of Five Compounds in Hedera rhombea using UPLC-PDA
- KMU-SS1303 Inhibit Osteoclastogenesis and Stimulate Chondrogenesis
- Lignans from Saururus chinensis Inhibit LPS-induced NO Production in Macrophage RAW 264.7 cells
- Perceptions of Investigators, IRB members, and IRB Administrators on the Procedure and the Bioethical Oversight System of National R&D projects
- Enhancement of Oral Absorption of Risedronate by Forming Ionic Complex with Bile Acid Derivative
- Characterization and Evaluation of Solid Self-emulsifying Drug Delivery Systems with Solid Carrier for Improved Simvastatin Release
- Research and Development of Cancer-targeting Nanomedicine
- The Role of NF-kB in Regulatory T cells and Autoimmune Diseases
- Awareness and Attitude of the General Public toward Personalized Pharmacotherapy in Korea
- Effect of Red Ginseng against Diabetic Neuropathy in Zebrafish
- Anti-cancer Effect of Tectochrysin in NSCLC cells through Overexpression of Death Receptor and Inactivation of STAT3
- The Apoptotic Effect of the Quercetin in Human Malignant Pleural Mesothelioma Cells through the Down-regulation of Specificity Protein 1
- Endocan Elicits Severe Vascular Inflammatory Responses in vitro and in vivo
- Chloroquine Down-Regulates Hypoxic HIF-1a level by Suppressing Translation of the Protein :a Potential Mechanism for Chloroquine-Mediated Chemosensitization
- Silybin Induces Cell-Cycle Arrest and Inhibits Melanoma Cell Growth by Direct Targeting of MEK1/2 and RSK2
- Design and Synthesis of Novel Lipophilic GCPII Inhibitors
- Identification and Synthesis of Sulfiredoxin Inhibitors for Anticancer Agents through a ROSmediated Mechanism
- Age- and UVB-induced mTOR Activation for Proinflammatory and Hyperpigmentary Mechanism through NF-κB and Autophagy Modulation
- Immunomodulatory and Hypoglycemic Effects of a New Herbal Preparation (HemoHIM) in Streptozotocin-Induced Diabetic Mice
- Novel bis-ortho-Alkoxy-para-piperazinesubstituted-2,4-dianilinopyrimidines (KRCA-0008) asPotent and Selective ALK Inhibitors for Anticancer Treatment
- Sphingosine-1-phosphate Induces C-reactive Protein via C/EBPβ and Promotes Breast Cancer Progression
- Tumor Microenvironmental Conversion of Natural Killer Cells into Myeloid-Derived Suppressor Cells
- Synthesis and Characterization of Transferrin Modified Mesoporous Silica Nanoparticles
- β-Secretase (BACE1)-inhibiting C-Methylrotenoids from Abronia nana Suspension Cultures
- Tyrosinase Inhibitory Phenolic Constituents of Smilax china Leaves
- A New Phenylethanoid Glycoside Isolated from Acer tegmentosum
- Matrix Metalloproteinases-1 Inhibitory Activity of Hydrolysable Tannins Isolated from Quercus Salicina
- KE-22, A Korean Traditional Herbal Formula, Inhibits Adipogenenic Differentiation of 3T3-L1 Cells
- Metabolomics Study of the Anti-depression Effect of Fluoxertine and Imipramine on Mouse Model with Chronic Mild Stress
- Constituents with DNA Topoisomerase Inhibitory Activity from the Aerial Parts of Agrimonia pilosa Ledeb.
- Preparation and Characterizations of BSA-loaded Bioadhesive PLGA Particles
- The Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs (ICH E14) and Analysis of ECG Database in Korean Population
- The Development Status of Cell Therapy Products in North-East Asia : The Cases of Clinical Trials in South Korea, Japan and China
- Prevention Plans of Medication Error in Pharmacy Practice
- Investigational Study of KGMP 5th Edition in Accordance with the International Pharmaceutical Regulation
- Development of Systematic Quality Control Method for Compound Herbal Medicine, KIOM-MA and Its Bioconversion Product, KIOM-MA128 by HPLC Chemical Finger Printing
- Effect of Interleukin-22 on the Epithelial Cell Transformation and Breast Tumorigenesis
- Anti-Helicobacter pylori and Antiulcerogenic Activities of Palmatine from the Root Cortex of Coptidis chinensis
- Constituents from the Leaves of Cryptotaenia japonica
- Dermal Absorption, Metabolism, and Pharmacokinetic Disposition of Phenoxyethanol in Rats
- Purification and Charicterization of a Novel Magnesium-independent Sphingomyelinase in Brain Mitochondria
- Preparation and in vitro Evaluation of Simultaneous Complexes for siRNA and Plasmid DNA based on the Optimized Conditions
- Glioblastoma Stem Cell Targeting PEGylated Immunoliposome Encapsulating Gemcitabine Conjugated with CD133 Antibody
- Charge-mediated Topical Delivery of Plasmid DNA with Cationic Lipid Nanoparticles
- Retrospective Analysis on Vitamin B12 Deficiency Anemia Patients
- Pharmacokinetics and Bioequivalence of Valsartan Tablet (Valsa V??) Prepared by Wet Granulation Method
- Cytotoxic Diterpenoid Pseudodimers from the Korean Sponge Phorbas gukhulensis
- Anti-inflammatory Effect of α-Viniferin in Raw 264.7 Cells from Clematidis Radix
- A Study on Importance-Performance Analysis of Pharmacy Preceptors’ Competencies after a Preceptor Education Program
- Pharmacotherapy for Pneumocystis pneumonia(PCP) in HIV-Infected Adults: Overview and a Clinical Case Report
- Regulation of Tobacco Products and Its Implications
- An Analysis of Comprehensive Evaluations by Pharmacy Students after Community Pharmacy
- Radio Frequency Identification (RFID) : New Trend in the Management of Distribution Medicine and Medical Supplies in Korean Pharmaceutical Industry.
- Selective Inhibition of the Function of Tyrosine-Phosphorylated STAT3 with a Phosphorylation Site–Specific Intrabody
- Sphingosylphosphorylcholine(SPC) Induced Invasion through Matrix Metalloproteinase-3 Upregulation in Breast Cells.
- Role of Neutral Sphingomyelinase 2 in Dopamine Transporter Trafficking
- Synthesis and Biological Evaluations of Novel Peptidomimetic Scaffolds as Anticancer Agents
- Ectopic Expression of ERbeta Is Sufficient to Inhibit Hypoxia-inducible Factor-1 Transactivation
- Chlorogenic Acid Inhibits Endotoxin-induced Inflammation in Murine Macrophages
- N-acetylcysteine Normalizes the Urea Cycle and DNA Repair in Cells from Patients with Batten Disease
- Comparative Study of Traditional Medicine Bojungikgitang in Korea, Japan and China on the Anti-Inflammatory and Anti-Oxidative effects
- Cognitive Enhancing Effects of Prunella vulgaris var. lilacina via Up-regulation of Hippocampal Neurogenesis
- Biofilm Inhibition and Antimicrobial Activity of Terpinen-4-ol Liposomes in Escherichia coli and Propionibacterium acnes
- Analysis of Antibacterial Spectrum of Rhus verniciflua
- High Payload Dual Drug-loaded Polymeric Micelles for Chemotherapy
- In vivo Assessment of TNF-related Apoptosis Inducing Ligand Encapsulated Microspheres for the Treatment of Pancreatic Cancer
- Application of Irradiation Technique to a Triamcinolone Acetonide Hydrogel for Topical Treatment
- Novel Triblock Fluorous Copolymer for Encapsulation of Amphotericin B
- Investigation for Notation of Tar Color Additives Used in Infant’s Drugs
- A Mixed Treatment Comparison of the Efficacy of Anti-TNF Agents in Rheumatoid Arthritis Patients with an Inadequate Response to a Traditional Disease Modifying Anti-rheumatic Drugs
- Evaluation of the Awareness Level for Animal Pharmacies among Pet Owners and Pharmacists
- Effects of P-glycoprotein and CYP3A4 Inhibition by Amlodipine on the Pharmacokinetic Parameter of Warfarin
- Novel Pro-Resolving Mediators in Inflammation & Infection
- Gα12 Gep Oncogene Inhibits FOXO1 in Hepatocellular Carcinoma by Deregulating miR-135b and -194
- Effects of Impurities on Stabilization of Amorphous Donepezil: Synthesis and Identification of Process-Induced Impurities of Donepezil.
- Licochalcone-based Bromo-retrochalcome Derivatives, SN159 as Dual Peroxisome Proliferatoractivated Receptor(PPAR) Alpha/Gamma Agonist.
- Discovery of Novel P2X7 Receptor Antagonists from Designing 2,5-Dioxoimidazolidine Based Constrained Structure of KN62
- Development and Validation of a HPLC/DAD Method for the Simultaneous Determination of Maker Components of Umbelliferae
- Pharmacokinetics Study of Nine Ingredients from Extract of Rhus verniciflua Stokes in Rats
- A New Triterpene Saponin from Tubers of Stachys sieboldii MIQ
- Therapeutic Phytomedicine Potential of Curculiginis Rhizoma by Suppressing Proinflammatory Cytokines on Reflux Esophagitis
- In Vitro and in Vivo Hepatoprotective Effect of Ganodermanontriol against t-BHP-induced Oxidative Stress
- Phytochemical Constituents from the Aerial part of Ducrosia ismaelis
- Marinopyrone A-E, New Secondary Metabolites from Marine-Derived Streptomyces sp.
- Enzalutamide Validation of Bioanalytical Method
- HPLC Analytical Method Development for Quantitative Determination of Impressic Acid in Acanthopanax Species
- Analytical Method Development for Screening and Confirmation of 67 Animal Drug Residues in Beef Using Ultra High Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry
- Concentrations of Rotenone in Vitreous Humor, Heart Blood, Peripheral Blood, Gastric Contents by Automatic SPE Procedure and LC/MS/MS in a Poisoning Case of Natural Biopesticide
- Marcepins A-E, New Peptides from Symbiotic Bacterium Serratia Marcescens Isolated from the Gut of the Dung Beetle Copris Tripartitus
- New Oxazolinate Secondary Metabolites of an Artic Actinomycete
- MR-3D Inhibits Catalytic Activity of Topoisomerase IIα and Induces G1 Arrest in Colon Cancer Cells
- Evaluation of Controlled Release Tablets of Paroxetine Hydrochloride Based on Polyethylene Oxide
- Transdermal Delivery of Tizanidine Hydrochloride: Effects of Various Vehicles and Enhancers
- Depletion of Glioblastoma Stem Cells Using Angiopep-2-conjugated Liposome Encapsulating γ-Secretase Inhibitor
- Sustained Effect of Wogonin-loaded Solid Lipid Nanoparticles on Apoptosis in MCF-7 Cells
- Enhanced Transdermal Drug Delivery of Tadalafil using a Novel Formulation
- Research on Exposure-Response Models to Predict the Clinical Outcomes of Drug Combination Therapy
- Inhibitory Effects of a New 1H-Pyrrolo[3,2-c]pyridine Derivative, KIST101029, on Activator Protein-1 Activity and Neoplastic Cell Transformation Induced by Insulin-Like Growth Factor-1
- Lysophospholipid and Their Receptors in the Nervous System
- Highly Enantioselective Phase-transfer Catalytic Alkylation of α-Halomalonates
- COT/Pin1 axis Promotes Tumorigenesis in Breast Cancer
- In Vivo Antibacterial Activity of New Oxazolidinones, LCB01-0699
- Mathematical-Model-Based Assessment of Streptozotocin-Induced Diabetic Rats: Whole-Body Level Glucose-Insulin Dynamics and β-Cell Functions
- Prevalence and Adherence of Medication Use among Pregnant Women: A Survey Study in South Prevalence and Adherence of Medication Use among Pregnant Women: A Survey Study in South
- Copper-Catalyzed Oxidative Esterification of 2-Carbonyl Substituted Phenols with Alcohols
- Development and Validation of a HPLC-MS/MS Method for the Quantitative Analysis of Twenty Urea Pesticides in Blood
- Crystal Structures and Thermodynamic Relationships of Tetramorphic Forms/Amorphous Form of Alzheimer's Disease Drug
- Pharmacological Chaperones Targeting Aberrant Protein-protein Interactions and Protein Instability
- MP-8 Shows Inhibitory Activity against Osteoclast Differentiation
- The Effects of 4-Hydroxybenzyl Methyl Ether on Memory Acquisition, Consolidation, or Retrieval Phase in Mice via the Activation of Dopamine D1 Receptor Signaling
- Phase-transfer Catalyzed Enantioselective Alkylation of α-Acetoxymalonates
- Absolute Configuration Determination of Pulvomycin and Pulvomycin Derivative Isolation
- Linalool and Linalyl Acetate Isolated from Agastache rugosa (Fisch. & Mey.) Kuntze Inhibits the Production of Macrophage-Derived Inflammatory Mediators
- Characterization of Novel Regulators of Helper T Cell Proliferation
- Inhibitory Effect of Rhododendron brachycarpum on Degranulation and Cytokine Expression in RBL-2H3 Cells
- HPLC-ESI-MS/MS Method for the Determination of Phenoxyethanol and its Active Metabolite, Phenoxyacetic acid, in Rat Plasma
- Analysis of Systemic Fluoroquinolone Use in Children in Korea
- Neuropeptides: Function in Colorectal Tumoringenesis
- Pathogenesis of IBD: the Roles of Gut Microbiota and Genetic Polymorphisms
- DOT1L Histone Methyltransferase as a Cancer Therapeutic Target
- New Role of Pif1 Helicase during DNA Double-strand Break Repair
- Dispensing Animal Medication at Pharmacies with a Veterinary Prescription
- Introduction to High-dimensional Massive Data and Recent Multivariate Statistical Tools
- Glycoproteome Profiling of Human Gaastric cancer Tissue using Filter Aided Capture and Elution and UPLC-MS/MS
- Major Considerations for the Drug Quality Review
- Polymorphic Variant of the CYP2A6, CYP2C8, CYP2D6, CYP3A5 in Korean Population
- Memorial Impairment in Estrogen Receptor α Knockout Mice
- The Possible Use of A3AR Agonist, LJ529, as Drug Therapy in Dementia by Proving Its Protection from ROS-induced Neurotoxicity and Memory Loss
- LJ 1, a Novel Derivative of the Natural Compound Deguelin, Promotes Inhibition of Proliferation in Vitro
- OF70E Counters Stress Responds in Zebrafish
- A Pilot Study to Evaluate Chemopreventive Effects of Blueberry (Vaccinium spp.)
- Placenta Derived Mesenchymal Stem Cells Improve Memory Dysfunction in an Aβ1-42-Infused Mouse Model of Alzheimer’s Disease
- Comparison of the Korean Genotypes from Pharmcogenotyping Method and Next Generation Sequencing/Direct Sequencing
- Preclinical Safety Evaluation of the CIA06-adjuvanted HPV L1 VLP Vaccine
- Safety Assessment of CIA05, a New Adjuvant for Human Vaccines
- Fatty Acid Composition of Adipose Tissues in Wistar Rats Fed with Gryllus bimaculatus Extract
- A Study on the Antigastritic Effects of Rheum Species Extracts and Their Active Components
- Natural Herbal-Based Novel Adjuvants: Stimulation of Humoral and Cell-mediated Immune Responses
- PKA Mediates Anti-angiogenic Activity of an Integrin α3β1-binding TIMP-2 Peptide in Human Umbilical Vein Endothelial Cells
- Identification of Annexin II as a Novel Secretory Biomarker for Breast Cancer
- NR1D1 Inhibits DNA Repair through Interaction with Poly(ADP-ribose) polymerase-1
- Neuroprotective Effect of Ethyl Acetate Fraction of KMU-PO1301
- Evaluation of Drug Delivery Profiles in Geometric Three-layered Tablets with Various Mechanical Properties, in vitro-in vivo Drug Release, and Raman Imaging
- Globular Adiponectin Suppresses Ethanol-induced ROS Production in RAW 264.7 Macrophages
- A New Flavan-3-ol from Bletialla striata
- Protective Effects of ES 70% EtOH Extract on Alcoholic Fatty Liver Induced Ethanol Diet Fed Rats
- Murine Gammaherpesvirus 68-Derived MiRNA Regulates Lytic Replication through c-JUNAssociated Signaling Pathway
- Nagative Regulation of Prolyl isomerase Pin1 on the Stability of SUV39H1 to Promote Tumorigenesis in Breast Cancer
- Regnase-1-Mediated Posttranscriptional Regulation of Inflammation
- Physical Pharmacy in 6-year Pharmacy Education
- The Impact of Medication Adherence on Health Outcomes for Chronic Metabolic Diseases: A Retrospective Cohort Study
- Multifunctionality of Nucleotides and Their Derivatives in Drug Delivery
- Dual Therapeutic-imaging Nanoparticles for Triggered Tumor Delivery of Chemotherapeutic Adjuvant
- Correlation of Skin Toxicity and Hypertension with Clinical Benefit in Advanced Hepatocellular Carcinoma Patients Treated with Sorafenib
- Current Regulation Issues of Generic Drugs
- Impact of Human Drug-Metabolizing Enzymes in Drug Development
- Anti-obesity Effects of Caulerpa okamurae Extract Are Characterized by Decreased Adipogenesis and Regulated Lipid Metabolism in 3T3-L1 Adipocytes
- Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors from Camellia japonica
- Block of Sodium Channel Nav1.7 by JSC1
- Effects of Decoction Water on Extraction of Components in Araliae Continentalis
- Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors from Morinda citrifolia (Noni) and Their Insulin Mimetic Activity
- Suppression of Adipose Inflammation and Macrophage Chemotaxis by Butein Protects against Glucose Intolerance in Mice Fed High Fat Diet
- The Signaling Mechanism of the PAR2-AP Induced Contraction in Cat Esophageal Smooth Muscle Cells
- SHARMA Kushal, NO Inhwan, YI Eunyoung Differentiation in Mouse Myoblast C2C12 Cells
- Dense Cell-Interior Ryanodine Receptors Associated with Invaginated Surface Membrane Transduce Fluid Pressure to Arrhythmogenic Ca2+ Wave in Atrial Myocytes
- The Citrus Fruits-derived Flavanone Hesperidin Suppresses Cell Growth through Direct Inhibition of Specificity Protein 1 in Human Malignant Pleural Mesothelioma
- RSK2-induced Stress Tolerance Enhances Cell Survival Signals Mediated by Inhibition of GSK3b Activity
- Synthesis of 3-(Diarylmethylene)oxindoles via a Tandem Reaction Combining Three Palladium-Catalyzed Reaction
- Palladium-Catalyzed Direct Acylation of Ketoximes and Aldoximes with Alcohols via C-H Activation
- An Extremely Alkaline Novel Chitinase from a Newly Isolated Streptomyces sp. CS495
- A Novel Biguanide Derivative HL-156A Inhibits Tumor Growth through AMPK-dependent Pathways in Human Breast Cancer
- The HDAC Inhibitor, LBH589 Induces Apoptosis through Regulation of Specificity Protein 1 Expression in Himan Oral Squamous Cell Carcinoma
- Anti-inflammatory Effect of 4-tert-butyl Phenyl Salicylic Acid in Lipopolysaccharides-Stimulated Raw 264.7 Mouse Macrophage Cells
- Synthesis of Characterization of Chalcone Derivatives for the Imaging of β-amyloid in Alzheimer Disease
- Anti-adipogenic Activity of the Edible Brown Alga Ecklonia stolonifera and its Constituent Fucosterol in 3T3-L1 Adipocytes
- Effects of Hwangryunhaedok-Tang, Montelukast Alone, and in Combination on MUC5AC Production in Human Airway Epithelial NCI-H292 cells
- Anti-proliferation Activity and Inhibition of Wnt/β-catenin Signaling Mediated by Plant Extracts in Human Colon Cancer Cells
- Chemical Composition of the Fermented Fruits of Prunus mume
- Inhibitory Properties of Selected Essential Oils against Escherichia coli and Staphylococcus aureus
- Antioxidant and Neuroprotective Effects of Kaempferol and Tannic Acid against 6-Hydroxydopamine-induced Oxidative Stress
- Development of Analytical Method for Phenolic Constituents in Geranium thunbergii
- Preparation and Evaluation of Medicinal Effect on Tablet Containing Hwangryunhaedok-tang
- Combination Effects of Banhabaekchulchunma-tang Water Extract and Montelukast on Inflammatory Response in BEAS-2B Cell
- Phenolic Compounds with IL-6 Inhibitory Activity from Akebia quinata
- Ecdysteroids from Achyrathes bidentata
- A New Noreudesmane-type Sesquiterpene from Alpinia oxyphylla
- A New NF-kB Pathway Inhibitor from Thuja orientalis
- Developed New Simultaneous Analytical Method for Quality Control of Angelica Decursiva (AD)by HPLC
- Gold Nano-platform to Control the Cell-to-Substrate Adhesions
- Systematic Review and Mixed Treatment Comparison of Biologic Drugs to Patients with Rheumatoid Arthritis Refractory to TNF-inhibitors: Analysis of ACR 20/50/70 and HAQ Scores.
- Exceptionally Stable Fluorous Emulsions as the Intravenous Delivery Media for Sevoflulane-Volatile Anesthetics
- Nano-mechanical Correlation with Drug Resistance of Ovarian Cancer Cells using AFM
- A Study on the Awareness of Current Medication and Dispensed Medication Analysis at Voluntary Pharmacy Service for Residents in a Region without Separation of Dispensary from Medical Practice
- Constructing Clinical Trial Databases of Gastrointestinal Tract Agents and Ailment Agents Including Medications of Fungal Infection, Skin Disease, Anemia and Thyroid Disease
- Modeling Supravalvular Aortic Stenosis Syndrome with Human Induced Pluripotent Stem Cells
- Structure of IP3 Receptor: Toward Understanding the Regulatory Mechanism
- High Dose of Cannabinoid CB1 Receptor Agonist, WIN 55,212-2 or ACEA, Induces Dopaminergic Toxicity in Mice; Implication of Protein Kinase Cδ Proteolysis
- Epigenetic Regulation of Glutamate Carboxypeptidase II by Valproic Acid in Human Astrocytes
- Inhibition of Protein Kinase Cδ Proteolysis by Liposome-encapsulated Melatonin Provides a Neuroprotection Against Trimethyltin-Induced Excitotoxicity in Mice
- Induction of Apoptosis by Tectochrysin in Colon Cancer Cell via Suppression of NF-κB Activity and Enhancement of DR Expression
- Neuropsychotoxic Potentials of Synthetic Cathinones in Mice: Comparison to Methamphetamine
- Kamolonol Potently Inhibits ROCK2 Activity and Suppresses Stress Fiber Formation and Cellular Hypertrophy in Angiotensin II-stimulated H9c2 cells
- Pharmacokinetic Drug-drug Interactions between Glimepiride and Piperazinedithioctate in Rats
- Pharmacological Evaluation of Honokiol Analogs in Murine Macrophages
- LRRK2-G2019S Interferes with Aggresome Formation by Suppressing Dynein Expression
- Influence of 12, 14-Labdantrien-18-oic Acid, a Component Isolated from Pinus densiflora Needle on Adrenal Catecholamine Release
- Apigenin Induces Cytotoxic and Autophagic Cell Deaths in Human Colon Cancer Cells
- Inhibitory Activity of Lichen Substance against Lung Cancer Cell Motility
- Anti-cancer Activity of Psw504 as a Down-regulator of HIF-1α-VEGF axis
- Anti-cancer Activity of Korean Mistletoe Lectin and Doxorubicin on Breast Cancer Cells
- IL-32γ-Mediated Cytotoxicity Exerts through Promotion of Granzyme B Secretion in NK Cells
- Discovery of Reversible Tyrosine Kinase Inhibitors for EGFR-T790M
- Inhibitory Effect of Abies koreana E.H. Wilson on Degranulation and Cytokine Expression in RBL-2H3 Cells
- Fluorescent Curcumin Derivatives as Probes Amyloid-beta Plaques in Alzheimer Disease
- Synthesis and Biological Evaluation of Non-hydroxamate Amide Compounds as HDACs Inhibitors
- Synthesis of Novel Fluorinated 5'-Deoxynucleoside Phosphonic Acid Analogues as Potent Antiviral Agents
- Asymmetric Synthesis of Hyacinthacine A2 via a Highly Regioselective and Diastereoselective Allylic Amination Using Chlorosulfonyl Isocyanate
- Simultaneous Analysis of Bioactive Metabolites from Kalopanacis Cortex by HPLC-ELSD-ESIQTOF-MS
- Design and Synthesis of Novel Carborane-containing CXCR4 Antagonists
- Anti-proliferative Activity of Hydnocarpin, a Natural Lignan, Is Associated with the Suppression of Wnt/β-catenin Signaling Pathway in Colon Cancer Cells
- Muurolane-type Sesquiterpenes from Marine Sponge Dysidea cinerea
- Transferrin-PEI Coated PLGA Nanoparticles for Codelivery of Doxorubicin and DNA
- Polyelectrolyte Complex Micelles by Self-assembly of Polypeptide-based Triblock Copolymer for Doxrubicin Delivery
- Enhanced Effect on Skin Permeability of Vitamin C Gel using Vibration Microneedle
- Stability and Compatibility of Paclitaxel Combined with Docetaxel in 0.9% Sodium Chloride Injection or 5% Dextrose Injection for Intravenous Infusion
- A Meta-Analysis of C-Reactive Protein as a Prognostic and Diagnostic Marker for Asthma
- Evaluation of Nutritional Parameter Change by TPN Therapy for Treatment of Early Malnourished Inpatients.
- A Study on the Perception of Community Pharmacist’s Role and Trust for Community Pharmacists
- Daumone Fed Late in Life Ameliorates Renal Aging in Mice
- Analysis of Anti-influenza Activity of Hedera helix Extract
- Dosage of Standard Herbal Decotion and Solid Extract
- New Tanzawaic acids from a Marine-Derived Fungus Peniciliium steckii 108YDC142
- Different Cytotoxic Effects of Polo-box Domain Inhibitors and ATP-binding Site Inhibitors Targeting PLK1 Activity
- Regulatory Perspectives in Off-Label Use
- Role of Cannabinoid CB1 Receptor on Methamphetamine-induced Dopaminergic Toxicity in Mice
- Design, Synthesis and Systematic Studies of Tetraazamacrocyclic Chelator for 64Cu-based Radiopharmaceuticals
- New Pyrimidine Derivatives Possessing ALK Inhibitory Activities
- Efficient and Regioselective Synthesis of 2,3-Disubstituted 6-Aminoquinoxaline Derivatives
- Multifunctional Effects of Honokiol as an Anti-inflammatory and Anticancer Drug in Human Oral Squamous Cancer Cells and Xenograft
- Innate Immune Receptors as Therapeutic Targets for Chronic Inflammatory Diseases
- Steroid 5α-Reductase Inhibition by Polymethoxyflavones from Black Ginger (Kaempferia parviflora) in Thailand
- The Development of Diabetic Retinopathy Therapeutic EG-Mirotin
- Pharmacokinetics of Finasteride in Rats
- MHY908, a Newly Synthetic PPAR α/γ Dual Agonist Attenuates ER Stress and Microinflammation in Aged Rats
- Traceless Solid-Phase Synthesis of 2,4,5-Trisubstituted Thiazole Derivatives
- Crystal Structure of Human c-Jun N-terminal Kinase 3 in Complex with Inhibitor
- Guideline on Review of the Fixed-Dose Combination Products for Cardiovascular Disease
- Non-toxic Endogenous Endosomolytic Nucleotides and Their Applications in Drug Delivery
- Flavonoidal Compound Derived from Chrysanthemum indicum L. Suppresses MUC5AC Mucin Gene Expression, Production and Secretion from Cultured Airway Epithelial Cells
- Selective Inhibitor of HDAC6 Induces DNA Damage and Apoptosis and Sensitizes Colon Cancer Cells to Anticancer Agents
- Stereoselective Total Synthesis of 1-Deoxygalactonojirimycin
- Pharmacokinetics and Biodistribution of Human Bone Marrow-Derived Clonal Mesenchymal Stem Cells
- Implementation Strategy of Specialized Pharmacy Services in a Healthcare Setting
- Using the Herbal Materal the Origin Identified
- The Mathematical Understanding for the 3-Dimensional Geometric Structure of the Basic Units Constituting Muscular Tissues
- Quantification of Homoegonol in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry and Its Pharmacokinetics
- Potential Therapeutic Anti-tumor Effect of a Salmonella-Based Vaccine
- Effects of Peucedanum japonicum Thunb Extraxt on the Inhibition of Acetylcholinesterase
- The Prevalence of Potentially Inappropriate Medication Use among Elderly in Korea
- Preclinical Assessment of Immunogenicity and Immunotoxicity of Stem Cells
- Effects of Platycodon Grandiflorum Root-derived Saponins, mainly Platycodin D, on Atopic Dermatitis-like Skin Lesions via Suppression of NF-κB and STAT1 and Activation of Nrf2/ARE-mediated HO-1
- Modulation of Heme Oxygenase-1 in Injured Muscle
- Preparation and in vitro Evaluation of Chitosan-coated Liposomal Delivery System for Risedronate
- Investigational Study of "Innovative Phamaceutical Companies in Korea": R&D Investment, Patent, and Manpower
- AMP-Activated Protein Kinase: a Key Regulator of Autophagy in Mycobacterial Infection
- Role of NRF2 in Photodynamic Therapy
- A Novel ALK5 Inhibitor, EW-7197 Inhibits Bile Duct Ligation-induced Hepatic Fibrosis Rat Model
- Apoptotic Effect of Honokiol on Human Malignant Pleural Mesothelioma via Modulation of Specificity Protein 1
- Antioxidant phenolic constituents from Parthenocissus tricuspidata
- Pharmacokinetics and Metabolism of Cryptopleurine, a Natural Product Isolated from Cryptocarya pleurosperma
- Survey of Tar Colors in Iron Preparations
- Effects of Anti-impotence Drugs on the Expression of Steroidogenic Genes in H295R Cells
- Prolyl Isomerase Pin1 Enhances Osteoblast Differentiation through Runx2 Regulation
- Design and Evaluation of Ondansetron Liquid Suppository for the Treatment of Emesis
- Anti-inflammatory and Anti-asthmatic Effects of Physails alkekengi Extract on Murine Cell Lines and an OVA-Induced Asthma Model of Mice.
- DNA Microarray Profiling of Genes Differentially Regulated by Three Heterochromatin Protein 1 (HP1) Homologs in Drosophila.
- Reversed-Phase High Performance Liquid Chromatography Method for Quantification of Cefatrizine Propylene Glycol in Pharmaceutical Formulation
- (2RS,4R)-2-(2,4-dihydroxyphenyl) Thiazolidine-4-carboxylic acid (MHY384) Suppresses Melanogenesis Induced by UV-induced NO/cGMP Signaling Pathway
- Induction of Human Leukemia Cell Differentiation via PKC/MAPK Pathways by Arsantin, a Sesquiterpene Lactone
- Discovery of a Novel Dual Inhibitor Targeting HER2 and Topo IIα via Down-Regulation of HER2 Transcriptional Level and Catalytic Activity of Topo IIα in Colon Cancer Cells
- Establishment of Active Chromatin Structure at Enhancer Elements by Mixed-lineage Leukemia 1 to Initiate Estrogen-dependent Gene Expression
- Anti-Proliferative Effect of Honokiol in Oral Squamous Cancer through the Regulation of Specificity Protein 1
- Determination of Fluoride in Dentifrice Marketed in Korea Using a Fluoride-Selective Electrode
- The Effect of Switching Over-the-Counter Drug (OTC) and Ethical Drug (ETC) on the Pharmaceutical Marketability in Korea
- Evaluation of Nutritional Parameter Change by TPN Therapy for Treatment of Early Malnourished Inpatients.
- Animal Models for Preclinical Efficacy Evaluation of Stem Cells Therapy
- Chemoprevention of Inflammation-Associated Colorectal Carcinogenesis: Molecular Targets and Underlying Mechanisms
- Dammarane Triterpenes from the Leaves of Panax ginseng Enhance Cellular Immunity
- Ameliorating Effects of Gynostemma pentaphyllum on Chronic Stress in Mice
- Modulations of Dopaminergic Signaling by Cathinone Derivatives in PC12 Cells
- In Vitro Effects of an Active Phyto-compound, MBT-2, on Immunoglobulin E-Mediated Type I Hypersensitivity
- Interrelation between Interleukin-6 and Ceruloplasmin in the Neuroprotection in Response to Kainic Acid-induced Excitotoxicity
- The Activation of Maternal Toll-like Receptor-2 Induces Broad Spectrum of Neuropsychiatric Problems in the Offspring
- Understanding the Conservation Patterns of Bovine CAPN1 at the Interaction Site with CAST:Insight from Trace Residues
- Cationic Pathway of Heck Reaction in a One-Pot Sequential Reaction of Three Palladium-Catalyzed Reactions.
- Synthesis and Biological Evaluation of Benzimine Compounds as Potential PTK6 Inhibitors
- New ρ-Aminoacetophenoic acids from the Marine Actinomycete, Streptomyces sp. SNM31.
- Study on Effect of Hand Sanitizers in Harmful Microbes and Skin Resident Flora
- Case Report of Pharmacist Intervention to Improve Medication Adherence
- Identification of Angelica Gigantis Radix by DNA Barcoding
- Activation of the NRF2 Pathway in Non-adherent Mammosphere Culture System
- Alpha-Synuclein-Induced Dysregulation of Neuronal Differentiatio
- Antibiotics Increases Absorption of Aspirin in Rat
- High-Throughput Screening of Six UDP-Glucuronosyltransferases Enzyme Activities in Human Liver Microsomes
- Analysis of Cinnamic Acid, Cinnamaldehyde and 2-Methoxycinnamaldehyde in Cinnamomi Ramulus on The Market in Seoul by HPLC
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