경부와 종격동에 발생한 캐슬만씨 병(Castleman's Disease)

• 영문명: Castleman's Disease of the Neck and Mediastinum
• 발행기관: 대한두경부종양학회
• 저자명: 남기현(Kee Hyun Nan) 최현호(Hyun Ho Choi) 임치영(Chi Young Lim) 이잔디(Jan dee Lee) 김승일(Seung Il Kim) 장항석(Hang Seok Chang) 홍순원(Soon Won Hong) 박정수(Cheong Soo Park)
• 간행물 정보: 『대한두경부종양학회지』제21권 제1호, 48~52쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2005.05.30

영문 초록

Objectives: Castleman's disease(CD) is a lymphoproliferative disorder of unknown etiology. To elucidate the clinicopathologic characteristics of CD, we retrospectively reviewed our experience. Methods: Fifteen patients with CD of the neck and mediastinum were identified. Patients were divided into two groups: group I had an unicentric CD and group II had multicentric CD. The histology of CD was divided into 3 subtypes: hyaline-vascular(HV), plasma cell(PC), and mixed. Results: The study included 12 cases of group I, 3 cases of group II in the clinical aspect and 10 cases with HV, 3 cases with PC, 2 cases with mixed type in the histologic aspect. Of group I patients who underwent complete surgical excision, all are currently free of disease. The clinical course of group II patients was variable. Of two patients with multicentric plasma cell CD who were treated, one remain free from disease and the other had a local recurrence in the neck. One patient with multicentric mixed CD died of disease after 30 months of presentation. Conclusion: Surgical resection is recommend for patients with the unicentric CD, regardless of histologic subtype. Patients with multicentric disease do not benefit from surgical resection and should be candidates for multimodality therapy.

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키워드

캐슬만씨 병 림프절 증식 질환 경부 종격동 Castleman's disease Lymphoproliferative disorder Neck Mediastinum