최소침습 갑상선절제술에서 피부절개전 Ketororac과 Bupivacaine 국소주사에 의한 진통효과

• 영문명: The Efficacy of Preincisional Surgical Site Infiltration of Ketorolac & Bupivacain in Minimally Invasive Thyroid Surgery: A Double Blind Study
• 발행기관: 대한두경부종양학회
• 저자명: 정웅윤(Woung Youn Chung) 김태진(Tae Jin Kim) 이해경(Hae Kyung Lee) 박정수(Cheong Soo Park)
• 간행물 정보: 『대한두경부종양학회지』제16권 제2호, 182~186쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2000.11.30

영문 초록

The reduction of the postoperative wound pain has been a concern in recent surgery, especially in various types of minimally-invasive surgeries. This study was performed to evaluate the postoperative analgesic effect of the preincisional local anesthesia with the mixture of ketorolac(Tarasyn) and bupivacaine to the surgical site in minimally-invasive thyroid surgeries. Of 491 patients who were scheduled for minimally-invasive thyroid surgeries between October 1999 and July 2000, 244 were randomly assigned to receive a mixture of ketorolac tromethamine 15mg(0.5ml) and 0.25% bupivacaine 3ml via surgical site infiltration 3 minutes prior to the skin incision. The outcomes of these patients were compared to those of the 247 controls. Total number of patients in need of post-operative analgesic requirements(n=39, 16.0%), total dose of postoperative analgesics used(19.6±8.4mg of ketorolac) and Visual Analogue Pain Score(VAS, 2.6±1.2) of the preincisional local anesthesia group were significantly lower than those of the control group(p 1.6±0.4 days for the preincisional local anesthesia group versus 1.9±0.7 days for the control group. The preincisional local infiltration of ketorolac and bupivacaine in the minimally invasive thyroidectomies reduces postoperative wound pain thus would be more beneficial to the patients.

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키워드

Minimally invasive thyroid surgery Ketorolac Bupivacaine Preincisional infiltration