Intramuscular administration of novel SLNs-loaded dual-reverse thermosensitive nanomicelle with sustained release and reduced toxicity
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- 발행기관
- 대한약학회
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- UD DIN Fakhar MEHMOOD YOUSAF Abid RASHID Rehmana MUSTAPHA Omer KIM Dong Wuk KIM Dong Shik KIM Jeong Hyeon YANG Eun Su TAK Jin Wook KIM Jong Oh YONG Chul Soon CHOI Han-Gon
- 간행물 정보
- 『춘계총회 및 학술대회』(2015년), 788~788쪽, 전체 1쪽
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- 의약학 > 내과학
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- 2015.04.24
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- Inhibitory effect of cudratricusxanthone A on human cytochrome P450
- Studies on the synthesis and mechanistic pathways of new 1-hydroxy-2-phenylindole compounds
- Development of computational alert system for preventing dosage-related errors to pediatrics
- Market analysis of narcotic analgesics in Korea using HIRA claims data
- Amitriptyline induced autophagy in SH-SY5Y cells
- Total Sythesis of (+)-Hyacinthacine A2 Using Chlorosulfonyl Isocyanate via Regioselective and Diastereoselective Amination
- Peroxiredoxin 3 negatively regulates ultraviolet B-induced apoptosis of epidermal skin
- IL-32θ inhibits cancer stem cell stemeness and epithelial-mesenchymal transition via STAT3 pathway in colon cancer
- Novel free-flowing fenofibrate-gelatin microcapsules with improved aqueous solubility : Preparation, physicochemical characterization and pharmacokinetics in rats
- Praeruptorin A inhibits in vitro migration of preosteoclasts and in vivo bone erosion : possibly due to its potential to target calmodulin
- Lactic acid bacteria isolated from Kimchi suppress intestinal allergic responses
- Reducing effect of estrogen on NF-κB driven amyloidogenesis in presenilin 2 mutatuion mice
- Protective effect of ultrasonicated processed ginseng berry extract on chronic ethanol-induced liver damage in rat model
- Chiral separation of proton pump inhibitors by capillary zone electrophoresis
- Phosphoinositol 3-kinase, a navel target molecule for the inhibitory effects of 5-hydroxy-1,4-naphthalenedione on TPA or EGF-induced cell trasformation
- IL-32θ inhibits cancer stem cell stemeness and epithelial-mesenchymal transition via STAT3 pathway in colon cancer
- Optimization of extraction method of functional components from a natural substance
- Total Synthesis of (+)-Neplanocin and Its Derivatives via Regioselective and Stereoselective Amination using Chlorosulfonyl Isocyanate
- Development of novel humanized therapeutic antibody targeting rheumatoid arthritis
- Characterization of GT as a drug repressing BACE1 expression in AD animal models
- Protein kainase C delta gene deficiency attenuates trimethyltin-induced neurotoxicity via up-regulation of Nrf2 and PI3K/Akt signaling pathway
- The role of cell adhesion on drug resistance of cancer cells
- In vitro and in vivo bone forming activity of Saururus chinensis extract
- A randomized clinical trial to examine the effects of ganglioside administration on gray matter volumes changes in the default mode network in individuals with subjective cognitive impairment
- “50th Anniversary of Invention Day” celebrated with launch of Korean Patent Guinness
- Analysis of national quality control of veterinary drugs in Korea via post marketing surveillance: a fifteen year retrospective study
- An Analysis of Consumption Patterns of High-Caffeinated Energy Drinks & Adverse Effects by Surveys from Students at Middle & High Schools in Korea
- Quantitative determination of DDP-1369, a new drug candidate for anti-parkinson’s disease, in rat plasma by LC-MS/MS, and its application to a pharmacokinetic study
- Involvement of the Nrf2/HO-1 signaling pathway in sulfuretin-induced protection against amyloid beta25-35 neurotoxicity
- Genistein, an inhibitor of Plk1, inhibits cell proliferation in cancer cells but not in non-transformed cells
- Portulaca grandiflora HOOK. suppresses inflammatory responses by blocking the NF-κB activation signaling pathways in BV-2 microglial cells
- Toxicological study for hydrogen cyanide, carboxyhemoglobin, ethyl alcohol and drug concentrations in postmortem blood specimens of the fire related fatalities
- Peroxiredoxin 2 has a protective function against ultraviolet B-induced skin photoaging
- In vitro anticancer efficacy of a multityrosine kinase inhibitor vandetanib
- Computational screening based on docking simulation and chemical similarity : Small molecules targeting LCK
- Modulation of nuclear receptor 4 A by amodiaquine
- Understanding of clinical trials and development of functional foods
- Association of apolipoprotein E (APOE) gene polymorphism with sporadic Creutzfeldt-Jakob disease (CJD)
- HIF-prolyl hydroxylase is a potential molecular target for topical minoxidil-mediated VEGF induction
- Instrumental analysis and quantification of beta-lactam antibiotic resistance in veterinary bacterial isolates
- Effects of metformin on breast cancer risk and mortality in patients with type 2 diabetes
- IL-32θ gene expression in acute myeloid leukemia suppresses TNF-α production
- Metabolic plasticity of adipose tissue and its therapeutic remodeling for healthy aging
- Interaction between N-terminal of lysyl-tRNA synthetase and C-terminal of laminin receptor studied by solution NMR
- National oncoventure, a new government R&D funding model for cancer drug development
- Studies on the effect of bile salt on the chemotherapeutic response of docetaxel-loaded thermosensitive nanomicelles
- Effect of sarpogrelate on high-fat diet-induced nephropathy
- Anti-colitic effect of the Anemarrhena asphodeloides and Coptidis chinensis mixture in mice with high fat diet-induced obesity
- Isolation of bioactive components from Cuscuta chinensis
- Chemical evaluation of marine sponge extract
- Licochalcone A from Glycyrrhiza inflate induces cell death through Specificity protein 1 signaling in oral squamous cell carcinoma
- Ecaluation of the efficacy and adverse effects of Dutatsteride with patient's therapeutic compliance
- Antimelanogenic effect of 2-methoxyphenyl-1-benzimidazole
- Strategies for the creation of core pharmaceutical patents utilized by underdeveloped space technologies
- Identification of in vitro noninvasive biomarkers for nephrotoxicity by proteomic analysis
- Molecular modeling & synthesis of b-raf inhibitor
- Affirmative impact of herbal medicine for various respiratory symptoms
- Hyaluronic acid-decorated poly(lactic-co-glycolic acid) nanoparticles for delivery systems of docetaxel and tanespimycin
- PEGylated lysozymes with anti-septic effects in human endothelial cells and in mice
- Identification and Characterization of Aroma Compounds in Cudrania tricuspidata (Carr.) Burea
- Bone resorptive activity of zinc ion-sustained releasing ZnO chips
- Enhanced biovailability and lymphatic delivery of paclitaxel-loaded lipid nanocapsules
- Synthesis, characterization and biological evaluation of oxadiazole derivatives bearing 5-phenyl-tetrazole as osteoclast differentiation inhibitors
- Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome for steatohepatitis
- Globular Adiponectin Causes Tolerance to LPS-induced TNF-α expression via Autophagy Induction in RAW 264.7 Macrophages: Involvement of ROS/FoxO3A Axis
- PTP1B inhibitory constituents from the aerial parts of Tradescantia spathacea Sw
- Young persimmon ameliorates obesity in leptin-resistant (db/db) genetically obese mice and affects adipose gene expression implicated in lipid metabolism and adipogenesis
- Evaluation of gastric motility activity of the extracts and isolates from traditional medicinal herbs
- Synthesis and biological activity of tricyclic derivatives containing a phenyl ring
- Metabolomic profiling of valproic acid-induced rat model of autism spectrum disorders using 1H NMR spectral analysis
- Coumarins from Angelica decursiva inhibit lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells
- Secondary metabolites of the aerial parts of Eclipta prostrata
- Two new compounds from the grains of Echinochloa utilis (Barnyard Millet)
- Pomolic acid inhibits invasion of breast cancer cells through the suppression of CXC chemokine receptor type 4 expression
- Green gold nanoparticles synthesized using earthworm extracts and the reinforcing effect on anticoagulant activities of heparin
- Effect of snail extract extract on chondrotin sulfate administration on growth increment, blood IGF-1, IGFBP-3 concentration in growing and old rats
- Chemical constituents from the leaves of Dryopteris erythrosora
- Picroside II extracted from Pseudolysimachion longifolium suppresses MUC5AC expression via downregulating p38/ERK MAPKs and modulating transcription factors in NCI-H292 human lung mucoepidermoid cells
- Hyperphosphorylation of tau in hippocampus in dab-treated mice might be associated with cognitive impairment
- Hepatoprotective Effect of Limonium tetragonum Extract Following Acute Alcohol Intoxicity in Rats
- Phenolic compounds from Salicornia herbacea
- Four New Bakuchiol Dimer Analogues from the Seeds of Psoralea corylifolia
- A polymeric colon-specific prodrug releasing 5-ASA and benzocaine ameliorates TNBS-induced rat colitis
- Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathway
- Synthesis of novel 4′ α -trifluoromethyl-2′ β -C-methyl-carbodine analogs as anti-hepatitis C virus agents
- Role of IL-32alpha as an anti-inflammatory cytokine in MOG-induced experimental autoimmune encephalomyelitis
- Antioxidant effect of Selenigella tamariscina methanol extract on impairments induced by scopolamine in rats
- Anoctamin1 (TMEM16A) is essential for testosterone-induced prostate hyperplasia
- Structural mechanism of ergosterol regulation and antifungal resistance by fungal sterol transcription factor Upc2
- Ilex paraguariensis increases capability to resist starvation stress in Drosophila
- Synthesis and biological activity of imide derivatives
- An LC–MS/MS method for the determination of imperatorin in human plasma
- Korean red ginseng inhibits myocardial toxicity by doxorubicin
- Reversal of breast cancer using an innovating nano-vehicle based on biocompatible polymers
- Two acidic amino acids, E143 and E705, contributes to calcium-dependent gating of Anoctamin 1
- Aqueous extract of Phyllostachyos Caulis in Taenian stimulates longitudinal bone growth in adolescent rats
- Distribution of CYP2C19*10 allele in a Korean population
- Inhibitory effect of a sesquiterpine from Schisandra chinensis on an ovalbumin-induced asthma model
- A new flavonoid and renoprotective activity of constituents from Sphagnum palustre
- Anisotropic biodegradable nanoparticles with enhanced capacity of surface ligand conjugation
- Protein tyrosine phosphatase 1B (PTP1B) inhibitory biflavonoids from Selaginella tamariscina
- Genetic Inhibition of Tyrosine Hydroxylase Potentiates Methamphetamine-Induced Neurotoxicity
- Shear stress enhances Ca2+ spark occurrence in rat ventricular myocytes via the activation of NADPH oxidase
- Studied on inducing hair restoration of synthetic Oleanolic acid derivatives
- Molecular modeling & synthesis of 11β-hydroxysteroid dehydrogenase type 1 inhibitor
- Drug repositioning: from anti-malarial drug to anti-obesity drug
- Catalase protects high-fat diet-induced early liver injury
- Antitumor activity of myriocin, a sphingolipid biosynthesis inhibitor, and its mechanism in melanoma mice
- Exogenous 8-oxo-dG prevents high fat-induced liver injury through enhancing mitochondrial biogenesis
- Attenuation of dbcAMP-induced Bad phospholylation in PC12 cells
- Comparison on tooth stain prevention effect of SAPP-contained mouthwash and others
- Signal transduction underlying the inhibitory mechanism of Fluoxetine on Electrical field stimulation response in rat ileal smooth muscle
- The inhibitory effect of SMB-6 on Rotenone induced endoplasmic reticulum stress and cell death in SH-SY5Y cells
- The influence of a CYP2C9 inhibitor on the pharmacokinetics of Meloxicam
- IL-4 mediated suppression of tumor development via activation of STAT6 in melanoma model
- Activation of NOX2 induces invasive phenotype in colon cancer cells through overexpression of MMP-7
- Delayed treatment with fenofibrate protects against high-fat diet-induced kidney injury via the AMPK-autophagy axis
- Prognostic gene signatures in pediatric medulloblastoma
- Species difference elucidation of 11β-hydroxysteroid dehydrogenase 1 through ensemble and induced fit docking studies
- Effect of the Conformational Restrictor in Benzamidochromenone derivatives for the inhibition of Interleukin-5
- A Aovel [3+3] Annulation Approach to Indolizines from the MBH Allyl Bromides
- Identification of inhibition modality of novel inhibitors for pim kinases using a fluorescence polarization assasy
- AME is a Mammalian Target of Rapamycin kinase inhibitor on EGF-induced neoplastic cell transformation
- Concentrations of benzodiazepines, hypnotics and sedatives in urine or blood forensic specimens related drug-facilitated crimes(DFC) in Korea
- Liquid chromatographic determination of creatine, dicyandiamide and dihydrotriazine in dietary supplements
- Nitric oxide-releasing poly(lactic-co-glycolic acid)-polyethylenimine nanoparticles for prolonged nitric oxide release, antibacterial efficacy and in vivo wound healing activity
- Chemical stability of bis-retinamido methylpentane, a novel hybrid retinoid derivative, and its in vitro and clinical efficacy
- Nitric oxide-releasing chitosan films for enhanced antibacterial activity and in vivo wound healing efficacy
- Quantitation of Biflorin in rat plasma by liquid chromatography–tandem mass spectrometry and its application to pharmacokinetic studies
- In vitro skin permeation of disodium phenyl dibenzimidazole tetrasulfonate using Franz diffusion cell method
- Tacrolimus-encapsulated porous poly(lactic-co-glycolic acid) microspheres for treating bleomycin-induced pulmonary fibrosis
- Synthesis of Antifungal Evaluation of 2H-[1,2,3]Triazolo[4,5-g]isoquinoline-4,9-diones
- Pathogenesis-related proteins (PRP) from a dropwort play a role in regulating toll-like receptor-dependent downstream signal pathway
- Improved pharmacokinetics and brain delivery of resveratrol from N-Trimethyl chitosan-g-palmitic acid surface modified solid lipid nanoparticles
- Facile and simple functionalization of gold and silver nanoparticles with ampicillin
- Inhibition of iNOS and cytokine induction by specific oligopeptides in fermented soybean extract from Glycine max
- Development and Evaluation of New Immediate-Release Dosage Form for Complex Migraine
- Chemical evaluation of marine sponge extract
- Strengthening immunity against influenza H1N1 virus by Morusalba L. fruit
- Chemotherapeutic potential of Hsp90 and biological evaluation of a novel Hsp90 inhibitor
- Requirements to be considered in the LIMS optimization process
- The Patents of material, the beginning of a new opportunity
- EGFR inhibitors for lung cancer therapy
- Process control strategy in biopharmaceutical manufacturing
- New alkaloids from roots and rhizomes of Veratrum nigrum L.
- Dual characterization of electroosmotic volume flow through skin and the modulation of ketoprofen flux using polyethyleneimine
- Discovery of microRNA as a potential biomarker for colorectal cancer metastasis
- Visible light-induced perfluoroalkylations
- Dapoxetine decreased the excitability of small dorsal root ganglion neurons
- Optimization of oligonucleotide synthesis using DOE Study
- Oxazolone as a useful synthetic tool for amidation of aminoisobutyric acid
- Flavonoid constituents from n-butanol fraction of the aerial parts of Agrimonia pilosa Ladeb
- Connecting the present and the future, Hanmi's R&D strategy
- Interspecies pharmacokinetic scaling of FL-05 based on animal data
- Efficient siRNA delivery system using dendritic gold nanoparticle
- Design and synthesis of 1,2,3,4-Tetrahydroquinoline-2-carboxylic acid N-(substituted) phenylamide derivatives as potential NF-kB inhibitor
- Studies on the mehanism of inhibition of serum and glucocorticoid-inducible kinases (SGKs) by a pyrrolopyridine derivative
- The role of tauroursodeoxycholic acid on stem cells for bone tissue regeneration
- Methionyl-tRNA synthetase (MRS) controls CDK4 stabiltiy in p16INK4a negative cancer
- Understanding and utilization plan of the product approval and patent linkage system – in the product patent viewpoint
- Alzheimer disease and treatment
- Advancement of pharmacy management and case
- Stability of glutamate carboxypeptidase II, a glutamate synthesizing enzyme, is regulated by acetylation
- State-of-the art characterization of biopharmaceuticals for QC/QA using advanced mass spectrometry
- Promotion criteria for clinical faculty in US pharmacy schools
- Biological effects of phenolic compounds isloated from marine algae
- Analysis of the mission and goal of pharmacy education
- Pharmaceutical care service, a crucial sector in national healthcare system
- PI3K-Targeting Fisetin Induces Apoptosis of Human B Lymphoma Raji Cells
- The Impact of Pharmacist-Initiated Interventions ImprovingAcute Coronary Syndrome Secondary Prevention
- MFDS biopharmaceutical quality and pharmacovigilance policies
- Development of laboratory monitoring alert system of hyperkalemia related to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers
- Bidirectional actions of hippocampal Zn2+ signaling in cognition: its involvement in amyloid-β-induced cognitive decline
- Glutathione peroxidase 1 deficiency attenuates Concanavalin A-induced hepatic injury by modulation of T-cell activation
- Modified delivery of axitinib that are nanohybrid liposomal nanoparticles effects on hypoxic tumor growth
- Pharmacokinetic study in disease animal model
- A pharmacokinetics study of drug-drug interaction between 5-fluorouracil, irinotecan and BST204, a purified ginseng dry extract, after interavenous and intraperitoneal injection administration to rats
- Effects of scutellarein, a flavonoid of Scutellaria lateriflora, on inflammatory responses
- Involvement of mTOR signaling pathways in the neuroprotective effect of Eleutherin against the glutamate-induced hippocampal cell damage, mimicking severe Alzheimer’s disease brain condition
- siRNA-ligand conjugate system for targeted delivery
- Effect of 18:1 lysophosphatidylethanolamine on intracellular Ca2+ concentration through GPCR in neuronal cells
- Prenatal toll-like receptor-2 activation induces social and cognitive problems in female mice
- Duel function of a novel compound E on platelet-derived growth factor-induced vascular smooth muscle cells
- Enrichment of cells with high-level protein expression by destabilization of selection marker
- Protective effect of 8-oxo-2'-deoxyguanosine in high fat-fed mice kidney
- Chrysin enhanced the therapeutic efficacy of docetaxel in non-small cell lung cancer
- Genetic mechanisms for association between tobacco smoking and allergy
- Preclinical assessment of toxicity and toxicokinetics of piroxicam after intra-articular injection in normal rats
- Rdiation induced cancer risk assessment via dietary exposure
- Inhibitory effect of Hinokitiol on adipogenesis in 3T3-L1 preadipocytes
- Kaaempferol suppresses collagen-induced platelet activation through inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation
- The prolyl isomerase pin1 interacts with a 90kDa ribosomal protein S6 kinase 2 to enhance TPA-induced cell transformation
- YP754 inhibits adipocyte differentiation via downregulation of PPAR-gamma in adipocytes
- Autophagic dysregulation by altered expression of novel autophagy regulators in Parkinson’s disease model
- Role of moesin in HMGB1-stimulated severe inflammatory responses
- PI3K-Targeting Fisetin Induces Apoptosis of Human B Lymphoma Raji Cells
- The interaction between Notch-1 and HIF-1α promotes ischemic neuronal death
- A novel PPAR pan agonist MHY2013 improves insulin-resistance and dyslipidemia in db/db mice
- Repositioning potential of PAK4 to osteoclastic bone resorption
- Anti-osteoclastogenic activity of p38 inhibitor doramapimod via inhibiting migration of pre-osteoclasts and NFATc1 activity
- Eukaryotic translation initiation factor, eIF2S2, promotes cell growth and migration in human cervix carcinoma cells
- Animal models for preclinical efficacy evaluation of stem cell therapy
- Solanum tuberosum L. cv Hongyoung extract inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice
- Increase of CCR7-dependent dendritic cell migration to lymph node by glucans
- Phaseollin inhibits endotoxin-induced inflammation in murine macrophages
- Rosmarinic acid inhibition of HIF-prolyl hydroxylase is potentiated by lipophilic modification of the natural product
- Target identification of thienopyrimidine derivatives by a chemical biology approach
- Studies on Phytochemical Constituents from Nandina domestica
- Attenuant Effects of Hydroponic-cultured Ginseng leaf extract on inflammatory collagen-induced arthritis in Rats
- Heat-processing of Corni Fructus enhances renoprotecive effect on cisplatin-induced acute kidney injury in mice
- Metabolism of evogliptin in human hepatic preparation
- Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced beta-cell damage and the development of type 1 diabetes
- Determination of the free thiol-containing antitumor agent, mertansine, in rat plasma by LC-MS/MS and its application to pharmacokinetic study
- Multiresidue method for the quantitation of 20 pesticides in aquatic products
- Role of cytochrome P450 and UDP-glucuronosyltransferases in metabolic pathway of homoegonol in human liver microsomes
- Method Development of NBOMes in Oral Fluid by Solid Supported Liquid Extraction and Gas Chromatography Mass Spectrometry
- Formulation,characterization and physicochemical evaluation of Melissa officinalis L. leaves tablets
- Sustained release Melt Extruded formulations using Eudragit RSPO and RLPO and content uniformity by FT-IR chemical imaging
- Continuous twin screw granulation and powder rheological characterization of dry granules containing levetiracetam
- Development and evaluation of orally disintegrating tablet by inclusion complex
- Particle design and in vivo evaluation of Eudragit E nanoparticle containing dutasteride
- In vitro and in vivo characterization of novel anti-AMF human monoclonal antibody for cancer therapy
- Preparation of taste-masked solid dispersion containing palonosetron hydrochloride and evaluation of taste-masking efficiency using E-tongue
- The degradation profile and pH stability of Tenofovir Disoproxil
- Application of physiologically based pharmacokinetic (PBPK) modeling in prediction of pediatric pharmacokinetics
- Population pharmacokinetic modeling of midazolam in healthy volunteers : evaluation for drug-drug interaction
- Effects of regulatory nuclear receptor (CAR, HNF4α and PXR) genetic polymorphisms on stable warfarin doses in patients with mechanical cardiac valves
- Application of Advanced Compartmental Absorption and Transit model for prediction of human pharmacokinetic(PK) profile uisng preclinical in-vitro and in-vivo studies
- Oxidative C7-Acylation of Indolines with Aldehydes or Alcohols under Palladium Catalysis
- Two new lignans from the Fruits of Schisandra chinesis(Turcz.)Baill
- The Improving effect of Cucumis melo on atopic dermatitis in vivo
- New cytotoxic sesquiterpenoids from siegesbeckia glabrescens
- Eriobotryae Folium improved inflammatory response through an oxidative stress and advanced glycation endproduct-meidated pathway in the liver of type 2 diabetic db/db mice
- Taming the chemical reactivity and selectivity : Known and unknown paths (and somewhere between)
- Effects of AGS to stress caused by climate change
- Evaluation of questions from Cybercondriacs related to drug information and suggestion of providing evidence-based answer
- In-vitro study of Novel Active Ingredient for Dentin Hypersensitivity Toothpaste
- PEGylation effect of poly(amidoamine) dendrimers on cytotoxicity in hippocampal neuronal cells
- Synthesis and Biological Evaluation of Chemical Probes Targeting Hypoxia-Inducible Factor (HIF)-1α/ Malate Dehydrogenase 2
- Dose-independent ADME properties and tentative identification of metabolites of a-mangostin from Garcinia mangostana in mice by automated microsampling and UPLC-MS/MS method
- Effects of geniposide on hepatocytes undergoing epithelial-mesenchymal transition in hepatic fibrosis by targeting TGFβ/Smad and ERK-MAPK signaling pathways
- Metabolomic application for MS based flavonoid research
- Protein tyrosine phosphatase 1B (PTP1B) inhibitory biflavonoids from Selaginella tamariscina
- Simultaneous analysis of creatine and creatinine in human urine by high-performance liquid chromatography
- A large-scale synthesis of self-assembled DNA nanostructures by rolling circle amplification for delivery of siRNA conjugates
- Antiproliferative and Apoptosis-Inducing Activities of 4-Isopropyl-2,6-bis(1-phenylethyl) phenol Isolated from Butanol Fraction of Cordyceps bassiana
- Para-methoxymethamphetamine (PMMA) induces neurotoxicity and memory impairments in mice
- Characterization of the auditory electrophysiological responses in rat with salicylate-induced tinnitus
- P47phox plays a critical role in the apoptosis and reactive microgliosis induced by methamphetamine
- IRAK4 as a therapeutic target of innate immunity-imbalanced acute liver injury by chlorogenic acid
- Hypoxia-inducible factor-1α upregulates tyrosine hydroxylase and dopamine transporter via nuclear receptor ERRγ in SH-SY5Y cells
- Anti-inflammatory Activities of Gouania leptostachya Methanol Extract and its Constituent Resveratrol
- Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice
- CYP2D6 genetic polymorphism significantly affects pharmacokinetics of Tolterodine
- The stereoisomers of crizotinib differentially induce change in the morphology of cancer cells
- Development of reactive metabolite screening system using human liver microsomes and LC-MS/MS
- Radiation human exposure and cancer risk assessment in cosmetics
- Evaluation of chemosensitivity using patient-derived xenograft model
- Ginseng total saponins induces the cardioprotection against ischemia/reperfusion injury
- Induction of integrin signaling by steroid sulfatase metabolism in HeLa cells
- A ring-truncated deguelin analogue induces apoptosis and anti-angiogenesis in non-small cell lung carcinoma cells
- Cristacarpin inhibits endotoxin-induced inflammation in murine macrophages
- Effects of apigenin and synthetic flavones on senescence-associated secretory phenotype in bleomycin-induced senescence in BJ fibroblasts and in vivo aged rats
- Apatinib in HSA-PEG inhibits VEGF-induced retinal vascular permeability
- Anti-inflammatory effects of Crataeva nurvala Buch. Ham. Are mediated via inactivation of ERK but not NF-κB
- Selective C–H Cyanation of Indolines and Indoles with Easily Accessible Cyano Source under Rhodium Catalysis
- Selective C–H Allylations of Indolines and Indoles with 4-Vinyl-1,3-Dioxolan-2-One under Rhodium Catalysis
- Chiral separation of evodiamine in the biological sample by HPLC
- Pharmacokinetics and therapeutic efficacy of piroxicam, a long acting non-steroidal anti-inflammatory drug, after intra-articular injection in osteoarthritis-induced rats
- Structure ensemble based virtual screening discovered new inhibitors of tyrosinase
- Preparation and evaluation of oral disintegrating film containing local anesthetic agent, Lidocaine
- Determination of drometrizole trisiloxane by LC-MS/MS and application to an in vitro dermal absorption study
- The Misuse or Abuse of Stimulant Medications for Attention-Deficit/Hyperactivity Disorder (ADHD) in Adolescents and Adults
- Acerogenin A, a natural compound isolated from Japanese folk medicine Acer nikoense Maxim, prevents oxidative stress-induced neuronal cell death through Nrf2-mediated heme oxygenase-1 expression
- The potent medicinal plants, species of Lycopodiopsida, as a therapeutic agent for non-alcoholic fatty liver disease
- 4-Isopropyl-2,6-bis(1-phenylethyl)aniline 1 originated from Cordyceps bassiana has anti-inflammatory activities in macrophages
- Development of standard criteria for the quality evaluation of The Gentianae Macrophyllae Radix by TLC and HPLC
- Influence of MRP2 C24T genetic variant on the pharmacokinetics of Valsartan
- Alleviation of ischemia and reperfusion-induced liver injury by SPA0355
- Increased neural stem cell proliferation by quercetin-3-O-glucuronide
- Preparation and physicochemical characterization of cocrystal comprising celecoxib and tramadol hydrochloride for improved intrinsic dissolution rate
- Anticonvulsive potential of glutathione peroxidase-1 against convulsive behaviors induced by cocaine
- Stereoselective total synthesis of 1-deoxygalactonojirimycin and research on total synthesis of 1-deoxyidonojirimycin via chiral 1,3-Oxazine
- Repositioning of Prickly Pears grown in Jeju Island for treatment of perimenopausal symptoms
- Design, synthesis, and biological evaluation of small molecule as hsp90 inhibitor
- Screening of Novel Monoamine Oxidase Inhibitors from Extracts of Lichens with Ethyl Acetate
- Drug development targeting Pin1-catalyzed conformational changes in cancer and Alzheimer’s Disease
- Beneficial effects of Humulus japonicus extract on hyperlipidemia and fatty liver induced by high-fat diet obesity
- Anti-cancer effect of (E)-4-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol on colon cancer cell growth by activation of DRs and inhibition of STAT3/NF-κB pathways
- Genetic inhibition of ceruloplasmin potentiates neurotoxicity induced by kainate
- Mitochondrial alteration and AMPK activation in NRF2-silenced human cancer cells
- Neuroprotective effects of WSY against lipopolysaccharide-induced neuronal damage
- 15-deoxy-Δ12,14-prostaglandin J2-induced cell apoptosis through ROS-mediated mechanism in gastric cancer cells
- In vitro activity of (-)-deoxypergularinine against Mycobacterium tuberculosis strains
- Hydroquinone suppresses expression of IFN- β via AKT regulation
- Potent and selective inhibition of sarpogrelate and its active metabolite, M-1, on the Human UDP-glucuronoslytransferase 1A4 activity
- Citrus unshiu peel extract protects cultured rat cortical neurons from beta amyloid-induced neurotoxicity
- Neuroprotective effects of labm99 on ischemia/reperfusion injury through inhibiting ASK1-JNK-p38 signal pathway
- Cordyceps pruinosa Buthanol fraction exhibit anti-inflammatory effect by suppressing of NF-kB activation
- 5-Aminosalicylic acid activates AMPK: an implication in anti-colitic activity of the anti-inflammatory drug
- Organic anion transporter 3-mediated transport of verproside
- Facile and Inexpensive microfluidic array chips for the detection of DNA/RNA pathogens
- Preparation of chitosan coated alginate-Bee Venom nanoparticles
- Quantitative analysis of sphingomyelin by high-performance liquid chromatography after enzymatic hydrolysis
- Inhibitory effects on gstric lesions of Genipin
- Trp250-hK2 is defective in intracellular trafficking and actives the unfolded protein
- Nrf2 regulates AhR activity, which contributes to cell survival
- Wound healing effect of the butanol fraction from Hydnocarpi Semen crude extract in ulcer injury of mice
- Aminopyridinol derivatives inhibit serotonin- and MDA-MB-231 human breast cancer-induced angiogenesis
- Idebenone, an ANO1/CaCC inhibitor found by High-throughput screening, has potential for use in cancer therapy
- In-silico search for putative drug candidates against melioidosis based on the crystal structure of sedoheptulose-7-phosphate isomerase
- Directions in convergent and creative pharmacy human resource development in terms of academia - focused on neuropharmacology
- Oxidative Allylation of Aromatic and α,β-Unsaturated Carboxamides with Allylic Carbonates under Ruthenium Catalysis
- Eco-friendly synthesis and catalytic activity of catechin-capped gold nanoparticles
- Quantitative analysis of trans-Anethole in Fennel seed by GC/MS
- HPLC-UV analysis of the ortho-phthaldehyde in disinfectant for quality control
- Lipid-Enveloped ‘Smart’ Polyelectrolyte Complex Nanoparticles for Highly Effective Combination Chemotherapy
- Dysfunctioned Tau by direct interaction with SOD1 G93A disrupts microtubule structure in axon
- Overview of polmacoxib (AcelexⓇ): Newly approved drug for osteoarthritis
- Evaluation of antioxidants in protein formulation against oxidative degradation using various biophysical analysis methods
- Reprogramming of human fibroblasts to neuronal precursor cells with plant stem cell-derived Molecule
- Effect of sarpogrelate on high-fat diet-induced nephropathy
- Melatonin effectively enhances aging indices by activating helper T cell signaling
- Mode Of Inhibition Of AXL Tyrosine Receptor Kinase by a heteroaryl Substituted Triazole Compound
- Roles of community pharmacists for pharmaceutical safety management
- Efficient DNA vaccination using chemoattractant loaded microsphere/polyplex releasing multi-layered microneedle
- Understanding of visible particulates and foreign insoluble matter test in biopharmaceutical product for international regulatory harmonization
- The critical role of negative feedback regulators in inflammation and host defense
- Development of Hot-Melt Extruded formulations with pressurized carbon dioxide
- Concise Synthetic Approach to Brazilin
- Effect of isoflavones on the lysosome and TFEB activity
- Connecting the present and the future, Hanmi’ s R&D strategy
- The March first independence movement of Chosun Pharmacy School students
- Discovery of active phytochemicals againts non-alcoholic fatty liver disease from Selaginella tamariscina based on dereplication using UPLC-DAD-QTOFMS
- Enhancement of Pharmacokinetic Profile and Antitumor Activity of Irinotecan using Polypeptide-based Block Ionomer Complex Micelles
- Inhaler Generic Development case - Fluterol Inhalation powder
- Identification and development of NamPT inhibitors as a synthetic lethal agent for NAPRT1-deficient lung cancers
- Inhibitory effects of Palmultang on inflammatory mediator production related to suppression of NF-kappaB and MAPK pathways and induction of HO-1 expression in macrophages
- A Novel compound from Antartic lichen restores cognition via suppression of inflammasome and BACE1 expression in Alzheimer’s disease mice
- Compound-14 isolated from Acanthopanax Root Bark inhibits inflammation by modulate the expressions of inflammatory marker via inactivation of MAPK pathway in murine macrophages
- Therapeutic effects of silibinin on the MPTP-induced Parkinson's disease model
- Simultaneous analysis of creatine and creatinine in human urine by high-performance liquid chromatography
- Comparative study between different kinds of membrane for in vitro permeation test with Franz' diffusion cells using minoxidil topical solution
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