당뇨 환자와 정상인의 스펙트럼 영역 빛간섭단층촬영을 통한 신경절세포-내망상층 두께 차이

• 영문명: Difference of GCIPL Thickness of Diabetes and Normal Eyes in Spectral Domain OCT
• 발행기관: 대한안과학회
• 저자명: 박상준 문연성 김나래,Sang Jun Park, MD, Yeon Sung Moon, MD, PhD, Na Rae Kim, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume55,number10, 1476~1480쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2014.10.15

영문 초록

Purpose: To analyze the difference of the ganglion cell-inner plexiform layer (GCIPL) thickness in diabetic and normal eyes of patients using spectral domain optical coherence tomography (OCT) (Carl Zeiss Meditec, Dublin, CA, USA). Methods: The authors compared and analyzed the difference of the GCIPL thickness measured with spectral domain optical coherence tomography (OCT) in 42 diabetic and 92 normal subjects. Results: The study subjects were divided into 3 groups: 92 normal subjects, 22 diabetic patients without diabetic retinopathy, and 26 diabetic patients with diabetic retinopathy. Presence of diabetes mellitus (DM) or diabetic retinopathy did not influence the retinal nerve fiber layer (RNFL) thickness. The GCIPL thickness tended to be thinner especially in the superior sector GCIPL. The GCIPL thickness of normal subjects, diabetes patients without diabetic retinopathy, and diabetic retinopathy patients was 82.24 ± 7.21 μm, 81.86 ± 9.53 μm, and 76.77 ± 14.13 μm, respectively, especially in the superior sector GCIPL (p = 0.029). Conclusions: Retinal ganglion cell layer thinning was induced by diabetes and diabetic retinopathy, and originated specifically from the superior part of the retina. J Korean Ophthalmol Soc 2014;55(10):1476-1480

키워드

Diabetes mellitus (DM), Ganglion cell-inner plexiform layer (GCIPL), Optical coherence tomography (OCT), Retinal nerve fiber layer (RNFL)