감염성 안질환의 원인균 및 항생제 감수성에 대한 10년간의 고찰

• 영문명: Cultured Organisms and Antibiotic Susceptibility in Infectious Ocular Disease: Results Over a Ten-Year Period
• 발행기관: 대한안과학회
• 저자명: 최현태 이동욱 안민 조남천 유인천,Hyun Tae Choi, MD, Dong-Wook Lee, MD, Min Ahn, MD, Nam Chun Cho, MD, In Cheon You, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number7, 934~940쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.07.15

영문 초록

Purpose: To investigate the ocular regional incidence, causative species and antibiotic susceptibility in patients with infectious ocular disease whose causative organism was isolated. Methods: A total of 519 eyes in 519 patients with infectious ocular disease, who were diagnosed by smears and cultures from January 2000 to December 2009 were retrospectively reviewed. Results: The mean age of the 519 patients was 54.0 years, and 66.1% of the patients were male. The most common systemic disease was diabetes mellitus. The most common previous ocular disease was keratoconjunctivitis. Specimens were most frequently swabbed from the cornea, where 81.2% were bacteria isolates and 18.8% fungi isolates. The most prevalent causative organism was Staphylococcus epidermidis, and the most prevalent fungus was Fusarium species. Vancomycin, ceftazidime, and fourth-generation fluoroquinolone maintained high antibiotic susceptibility. Methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus epidermidis were increasing near the end of the reference period, and endophthalmitis was more common in methicillin-resistant Staphylococcus. Conclusions: Identifying the causative organism in infectious ocular disease by smears and cultures is essential. More effective treatment of infectious ocular disease would be possible by analyzing the frequent organism, clinical manifestations, and antibiotic susceptibility. More caution is necessary due to the increase in methicillin-resistant Staphylococcus. J Korean Ophthalmol Soc 2012;53(7):934-940

키워드

Antibiotic susceptibility, Cultured organisms, Infectious ocular disease, Methicillin-resistant Staphylococcus