허혈성 망막중심정맥폐쇄에서 유리체내 베바시주맙 주입 후 임상경과

• 영문명: Clinical Course after Intravitreal Bevacizumab Injection in Ischemic Central Retinal Vein Obstruction
• 발행기관: 대한안과학회
• 저자명: 유은석 유영주 최문정 한정일 유수진 이동원 조성원 김철구 이태곤 김종우 이재흥
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume52,number10, 1202~1207쪽, 전체 6쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2011.10.15

영문 초록

Purpose: To determine the clinical outcome of intravitreal bevacizumab injection in patients with ischemic central retinal vein obstruction (CRVO). Methods: The present study was conducted retrospectively on 56 eyes of 56 patients who were diagnosed with CRVO and classified according to ischemic and non-ischemic type and underwent an intravitreal bevacizumab injection. The present study measured changes in visual acuity and central macular thickness, neovascularization in the anterior segment, development of neovascular glaucoma and other clinical complications. Results: The average number of bevacizumab injections in both groups was 2.07 and 1.62 in the ischemic type. No patients developed neovascular glaucoma in the non-ischemic type group, 14 of 26 eyes in the ischemic type group developed neovascular glaucoma and the mean time to diagnosis was 28.75 weeks. log MAR visual acuity of the ischemic type group prior to injection was 1.56 ± 0.65 on average which improved to 1.44 ± 0.97 (p = 0.45). Conclusions: Intravitreal bevacizumab injection improves the condition of cystic macular edema clinically, but does not affect the development of neovascular glaucoma and improvement of visual acuity in ischemic type CRVO. J Korean Ophthalmol Soc 2011;52(10):1202-1207

키워드

Central retinal vein obstruction, Intravitreal bevacizumab injection, Neovacular glaucoma