신생혈관녹내장에서 항대사제를 병용한 아메드 장치 삽입술의 수술 성공률 평가

• 영문명: Ahmed Valve Implantation with Adjunctive Mitomycin C and 5-Fluorouracil: Outcomes at One Year
• 발행기관: 대한안과학회
• 저자명: 윤헌주 박준정,Heon Ju Yoon, MD, Jun Jeong Park, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume51,number2, 227~233쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.02.15

영문 초록

Purpose: To evaluate the outcome after Ahmed valve implantation in patients with neovascular glaucoma when using intraoperative mitomycin C (MMC) and postoperative 5-fluorouracil (5-FU). Methods: A total of 40 eyes of 40 patients with neovascular glaucoma who received antiglacomatous medication without previous glaucoma surgery were included in the present study. The patients received Ahmed valve implantation and intraoperative MMC and postoperative 5-FU. Failure was defined as the first occurrence of any of the following: 1) the first of three consecutive visits where intraocular pressure (IOP) was ＞18 mmHg or 20% IOP reduction from baseline and the final number of topical medication did not reduce by at least two from baseline, 2) the need for additional surgery, or 3) the occurrence of a serious complication. Results: The cumulative success rate was 77.5% at 12 months. The final number of topical medication after Ahmed valve implantation was 0.73±0.78, and the change in the number of medication from baseline was -2.18±0.84. Serious complications such as endophthalmitis, valve exposure or prolonged hypotony were not observed . Conclusions: The adjunctive use of intraoperative MMC and postoperative 5-FU with Ahmed valve implantation results in a high success rate and good IOP control and did not show serious complications within the postoperative period. J Korean Ophthalmol Soc 2010;51(2):227-233

키워드

Ahmed valve implantation, Complication, Neovascular glaucoma, Success rate