양측 부신 절제술의 수술 후 결과 분석

• 영문명: Surgical Outcomes of Bilateral Adrenalectomy
• 발행기관: 대한내분비외과학회
• 저자명: 강보라 김지영 최준호 김지수 남석진 양정현1 김정한 Bo Ra Kang Jiyoung Kim Jun-Ho Choe Jee Soo Kim Seok Jin Nam Jung-Hyun Yang1 Jung-Han Kim
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』13권4호, 234~238쪽, 전체 5쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2013.12.30

영문 초록

Purpose: Because the main drawback of bilateral adrenalectomy is permanent adrenal insufficiency and the subsequent risks of life-long steroid use, adrenal preserving partial adrenalectomy is being accepted as its alternative. The aim of this study is to investigate the indications for bilateral adrenalectomy and to assess the postoperative outcomes and steroid replacement according to operative methods. Methods: From May 1996 through July 2013, a total of 25 patients who underwent bilateral adrenalectomy in our institution were reviewed retrospectively. Surgical outcomes were compared between total and partial adrenalectomy, and postoperative steroid hormone replacement were examined according to the volume of remnant adrenal gland. Results: The median follow-up duration of 25 patients was 55.8 months. The most common indication for bilateral adrenalectomy was bilateral pheochromocytoma (n=16), which was associated with genetic mutation of RET or VHL gene in 11 cases. Cushing's syndrome (n=8) and hyperaldosteronism (n=1) were another indications of bilateral adrenalectomy. Total adrenalectomy was performed in 8 patients and adrenal preserving partial adrenalectomy in 17 patients. Among the 17 patients, only 5 patients needed adrenal hormone replacement and 2 patients had a recurrence at remnant adrenal tissue. Conclusion: Adrenal preserving partial adrenalectomy might be a better option for bilateral adrenal tumor than total adrenalectomy because it can reduce complications associated with adrenal insufficiency and recurrence of the disease is not common.

키워드

양측 부신 절제술, 부신 전절제술, 부신 부분절제술,Bilateral adrenalectomy, Total adrenalectomy, Partial adrenalectomy