악성 종양의 추적 관찰 중 PET-CT에서 발견된 갑상선의 우연종

• 영문명: Incidental Findings of Thyroid Detected by PET- CT during Cancer Follow-up
• 발행기관: 대한내분비외과학회
• 저자명: 김중석 최소영 노효근 김세중 김윤정¹ 현인영² 김영모³ 조영업 Joong Suck Kim M.D. So-young Choi M.D. Ph.D. Hyo Keun No M.D. Sei Joong Kim M.D. Ph.D. Youn Jeong Kim M.D. Ph.D.¹ In Young Hyun M.D. Ph.D.² Young Mo Kim M.D. Ph.D.³ and Young Up Cho M.D. Ph.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』10권4호, 249~255쪽, 전체 7쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2010.12.30

영문 초록

Purpose: The incidence of thyroid cancer is increasing in Korea, partially owing to the development of diagnostic tools. Positron emission tomography (PET)-computed tomography (CT), in particular, has generally been used for evaluation of metastasis and follow-up of malignancy. Methods: We retrospectively investigated 2,833 patients with PET-CT for metastasis work-up or cancer follow-up, which was performed between January 1998 and May 2008 at Inha University Hospital. Of them, abnormal thyroid findings were discovered in 181 patients and we studied the result of further evaluation or follow-up PET-CT. Results: Thyroid cancer was diagnosed in 26 patients, including metastatic cancer in 3 patients, and non-operated primary cancer in 2 patients. Other 21 patients received operation, which in all histopathologically revealed papillary carcinoma. The mean age of the 21 patients was 55.4 years. Nine patients had a history of radiotherapy. The site of malignant nodule was discordant between PET-CT and histopathologic result in 6 patients. The mean size of malignant nodules was 9.45 mm (0.1∼23 mm) with microcarcinoma in 10 patients (47.6%). The mean interval between diagnoses was 15.8 months, and in 4 patients operations for two malignancies were performed in a same day. The incidence of thyroid cancer was significantly high in female patients, but the differences of incidence among different cancer groups were not significant for female patients. Conclusion: Early diagnosis of synchronous or secondary thyroid cancer by PET-CT in cancer patients can make early treatment and better strategies for multiple malignancies possible. (Korean J Endocrine Surg 2010;10:249-255)

키워드

갑상선암, 양전자단층촬영술, 우연종,Thyroid cancer, Positron emission tomography, Incidental findings