건강에 영향을 주는 주변환경의 미생물 오염 실태

• 영문명: Assessment of Bacterial Contaminations of the Surrounding Environment which Influences to Health
• 발행기관: 대한약학회
• 저자명: 김미진(Mi Jin Kim) 이도경(Do Kyung Lee) 장석(Seok Jang) 김정래(Jung Rae Kim) 안향미(Hyang Mi An) 백은혜(Eun Hye Baek) 이강오(Kang Oh Lee) 하남주(Nam Joo Ha)
• 간행물 정보: 『약학회지』제53권 제4호 (2009년), 194~200쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2009.08.31

영문 초록

Community-acquired antimicrobial resistant bacteria are an emerging problem whole world-wide. Generally, Hands are main mediator of pathogen transmission as compared with other body parts. So, the purpose of this research was to investigate the microbiological quality and antimicrobial susceptibilities of samples which were collected from the door knob and surface in public- and home-facilities, and also hand. Of total 191 samples, 71 samples (37%) were shown to be of high-level total bacterial count (>108 CFU/cm2). And presence of Staphylococcus and Enteric bacilli was observed in 61 samples (32%) and 76 samples (40%), respectively. Antimicrobial susceptibilities of staphylococcal isolates from the samples were tested for six different antimicrobial agents, which are in wide spread clinical use in Korea, as well as four new antimicrobials, daptomycin, linezolid, uinupristin/dalfopristin and tigecycline. Among staphylococcal isolates, antimicrobial resistance were observed in oxacillin (n=6), mupirocin (n=7), vancomycin (n=1), quinupristin/dalfopristin (n=2) and gentamicin (n=5). Fortunately, all the isolates were susceptible to new antimicrobial such as daptomycin, linezolid and tigecycline. Furthermore 4 Enterococcus faecalis were isolated from four hand samples, and all these isolates exhibited multidrug resistance to four different antimicrobial (oxacillin, quinupristin/dalfopristin, mupirocin, gentamicin). Also, 5 Escherichia coli were isolated from surface in home (n=3), door knob in public facilities (n=1) and hand (n=1). Escherichia coli isolated from hand was high-level resistant to tigecycline (128 μg/ml) and gentamicin (64 μg/ml).

키워드

antimicrobial resistance bacterial contaminations Staphylococci Enterococcus faecalis Escherichia coli