DMSO-Oxalyl Chloride에 의한 당의 산화

• 영문명: DMSO-Oxalyl Chloride for the Oxidation of Carbohydrates
• 발행기관: 대한약학회
• 저자명: 천문우(Moon Woo Chun)
• 간행물 정보: 『약학회지』제27권 제2호 (1983년), 181~184쪽, 전체 4쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 1983.06.30

영문 초록

DMSO-oxalyl chloride at low temperature in methylene chloride reacted with isolated secondary hydroxyl groups in some monosaccharides to give alkoxysulfonium salts, convertible to carbonyls in high yields upon addition of triethylamine. And 1,2:5,6-di-O-isopropylidene-alpha-D-allofuranose which is the key intermediate in the synthesis of 3-0-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide, was also obtained by oxidizing 1, 2:5, 6-di-O-isopropylidene-alpha-D-glucofuranose with the oxidizing reagent, followed by reduction with sodium borohydride.