척색종의 방사선 치료

• 영문명: Radiation Therapy of a Chordoma of the Thoracic Vertebra: Case Report and Review of Literatures
• 발행기관: 대한방사선종양학회
• 저자명: 김주영(Joo Young Kim) 최명선(Myung Sun Choi)
• 간행물 정보: 『대한방사선종양학회지』제6권 제2호, 295~300쪽, 전체 6쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1988.12.30

영문 초록

Chordoma is a malignant tumor arising from the primitive notochord involving the axial skeleton. It usually occurs at sacrococcygeal and basisphenoidal area but only rarely dose at other vertebral areas, especially at the thoracic vertebrae. It has a slow growth rate and is locally aggressive with an extremely high rate of local recurrence. Either surgery or radiation alone often fails to cure the disease and the local failure is the main cause of treatment failure and death, Overall 5 year survival rate is less than 10%. Useful palliation or occasional cure can be obtained by the combination of surgery and radiotherapy. After incomplete resection, the tumor requires radiation dose of 7,000 cGy or more over 6-7 weeks for local control. Tumor regression is slow in response to irradiation and continuation of the regression for several months after completion of RT is not unusual. We report a case of chordoma of the thoracic vertebra, the sith of extreme rarity, which showed good local control after partial resection and radiation therapy. He is well and alive without any evidence of recurrence after 13 months of treatment with near complete tumor regression.

키워드

Chordoma Thoracic vertebra Radiation therapy