한국인 대장암 및 유방암 사망의 장기추세 : 출생코호트 효과?

• 영문명: Mortality Trends in Colorectal Cancer and Breast Cancer in Korea : Birth Cohort Effects?
• 발행기관: 한국역학회
• 저자명: 전재관(Jae-Kwan Jun) 김연주(Yean-Iu Kim) 곽진(Jin Gwack) 최윤희(Yun-Hee Choi) 홍윤철(Yun-Chul Hong) 유근영(Keun-Young Yoo)
• 간행물 정보: 『한국역학회지』한국역학회지 제27권 제1호, 154~162쪽, 전체 9쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2005.06.01

영문 초록

Purpose : Cancer has been the leading cause of deaths since 1980s in Korea. Among them, colorectal cancer and breast cancer shows steadily increasing pattern, being the fourth and the fifth common site of cancer death in Korea, respectively. This analysis aimed to evaluate potential contribution of birth cohort effects to the recent increases in mortality of colorectal cancer and breast cancer since 1983 in Korea. Methods : Mortality statistics on deaths of both cancers for the past 20 years of 1983~2002 were obtained from the National Statistical Office. The age-standardized mortality rates were calculated based on the census population of 1992 as a standard. Results : Age-standardized mortality rate for colorectal cancer increased 4.7-fold in men and 3.6-fold in women, whereas 2.1-fold increase in breast cancer mortality during 1983~2002. Age-specific mortality rates for colorectal cancer were steadily increasing by age before 1991 in both genders. However, the mortality rates showed an exponentially increasing pattern for the age group of 70 and over during 1993-2001, which was more prominent in female. The birth cohort curves showed that there were 2- to 3-fold increases in the mortality rates of people who were born in 1931 for colorectal cancer compared to those of people who were born in 1921. Differences in mortality for breast cancer by birth cohort were 1.7-fold among age group of 45~49 and 50~54 between 1936 and 1946. Conclusions : This analysis suggests that recent increases in mortality of colorectal cancer and breast cancer could potentially be due to birth cohort effects, i.e. rapid changes in life-style in younger generation. The quantitative approach using age-period-cohort model should be pursued.

목차

서 론

연구대상/재료 및 방법

연구성적

고 찰

참고문헌

Abstract