탄저병의 개요

• 영문명: Anthrax : An Overview
• 발행기관: 한국역학회
• 저자명: 임현술(Hyun-Sul Lim) 송영구(Young-Goo Song) 유한상(Han-Sang Yoo) 성원근(Seong-Won Keun) 김종완(Jong-Wan Kim)
• 간행물 정보: 『한국역학회지』한국역학회지 제27권 제1호, 12~25쪽, 전체 14쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2005.06.01

영문 초록

Human anthrax has been a zoonotic disease affecting those who have close contact with animals or animal products contaminated with the spore-forming bacterium Bacillus anthracis. Now the incidence of anthrax in herbivores and human are rare, but it remains an important health problem in Korea because anthrax is seen as one of the most likely biological weapon. The B. anthracis forms a spore, which is resistant to drought, heat and numcrous disinfectants, and the spore can remain viable and infective in the environment for decades. There are three major forms of human disease depending on how infection is contracted, cutaneous, inhalation and ingestion. Inhalational anthrax is the most common from, but the events in the Korea show that gastrointestinal anthrax is the most common. Several cases of anthrax have been reported in Korea. In recent years, 2 cases of bovine anthrax and 5 cases of human anthrax occurred in Changnyeong-gun, 2000, but it haven't occurred any more so far. The most useful microbiological test remains the standard blood culture. Confirmatory diagnostic tests such as polymerase chain reaction can also be used and may help in early diagnosis. Prompt clinical suspicion and rapid administration of effective antimicrobials are essential for treatment of anthrax. Ciprofloxacin or doxycycline should be used for initial intravenous therapy until antimicrobial susceptibility results are known. The best measure to eliminate human anthrax is control in domestic animals by effective surveillance and by immunization of animals in endemic areas. Also, the government must establish countplan for knowledge and rational policies in dealing with potential bioterrorism attacks.

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참고문헌

Abstract