폐 다형암의 인두 후벽 전이: 근치적 국소 치료 후 장기 관해

• 영문명: Posterior Pharyngeal Wall Metastasis of Pleomorphic Lung Carcinoma: Long-Term Remission following Curative Local Treatment
• 발행기관: 대한두경부종양학회
• 저자명: 김지원(Ji Won Kim) 이윤정(Yun Jeong Lee) 김상흔(Sang Heun Kim) 이수민(Sumin Yi) 구본석(Bon Seok Koo) 장재원(Jae Won Chang)
• 간행물 정보: 『대한두경부종양학회지』제41권 제2호, 33~41쪽, 전체 9쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2025.11.30

국문 초록

Oropharyngeal metastasis from non-small cell lung carcinoma (NSCLC) is rare, particularly to the posterior pharyngeal wall (PPW), and can mimic head and neck neoplasms. A 78-year-old man with globus had a 2×3 cm PPW mass and a synchronous left upper-lobe lesion; biopsies from both revealed poorly differentiated pleomorphic carcinoma. Stereotactic body radiotherapy (SBRT; 60 Gy/4 fractions) to the lung achieved regression, and the PPW tumor was resected via transoral robotic surgery (TORS) with negative margins. Pathology confirmed metastatic pleomorphic carcinoma with thyroid transcription factor-1 (TTF-1) positivity and a high proliferative index. Ten months later, right level IIa nodal metastasis was excised by modified radical neck dissection; the node showed squamoid change with loss of TTF-1, and no human papillomavirus or tonsillar primary was identified. Without systemic therapy, the patient remains disease-free 5 years after TORS and 8 years after SBRT, supporting curative-intent local therapy in oligometastatic NSCLC.

목차

Introduction

Case presentation

Discussion

Acknowledgments

References

키워드

Head-neck surgery Oligometastatic lung cancer Oropharyngeal metastasis Pleomorphic carcinoma Transoral robotic surgery

참고문헌

• Mol Clin Oncol
• Eur Rev Med Pharmacol Sci
• Medicine (Baltimore)
• Respirol Case Rep
• J Clin Exp Dent
• Iran J Radiol
• Clin Respir J
• Int J Clin Exp Pathol
• Thorac Cancer
• Oral Oncol