Long-term Chemotherapy Management in a Small-breed Dog with Intracranial Invasive Nasal Carcinoma: A Case Report

• 발행기관: 한국동물보건학회
• 저자명: Min-Hee Kang
• 간행물 정보: 『한국동물보건학회지』4권 3호, 205~214쪽, 전체 10쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2025.09.30

국문 초록

A 7-year-old spayed female Shih-Tzu was presented with a one-year history of progressive sneezing and nasal discharge, followed by the recent onset of cluster seizures. Magnetic resonance imaging (MRI) revealed a right-sided nasal mass extending through the cribriform plate, with pachymeningeal enhancement suggestive of intracranial invasion. Rhinoscopic examination identified a hypervascular mass within the right nasal cavity, from which biopsy samples were obtained. Histopathological analysis confirmed a diagnosis of nasal carcinoma. The dog was treated with carboplatin-based chemotherapy and oral piroxicam, along with antiepileptic therapy. Follow-up MRI performed seven months after the initial evaluation showed complete resolution of the meningeal enhancement, despite an increase in the size of the nasal mass. Neurological function remained stable, and quality of life was preserved for over 16 months. This case illustrates the feasibility and potential benefit of long-term palliative chemotherapy in small-breed dogs with advanced nasal carcinoma involving intracranial extension.

목차

1. Introduction

2. Case Report

3. Discussion

4. Conclusion

Acknowledgement

Conflict of Interest

Orcid

References

키워드

Nasal carcinoma Dog Intracranial invasion Chemotherapy Piroxicam