해조류 추출물의 우치 미백 효과와 셀프 성형 트레이를 활용한 치아미백 임상시험 연구

• 영문명: Tooth Whitening Effects of Seaweed Extracts on Bovine Incisors and a Clinical Trial Using a Self-Forming Tray System
• 발행기관: 한국구강보건과학회
• 저자명: 박충무(Chung-Mu Park) 윤현서(Hyun-Seo Yoon)
• 간행물 정보: 『한국구강보건과학회지』제13권 제3호, 108~116쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2025.09.30

국문 초록

Objectives: This study aimed to evaluate a natural, seaweed-based tooth whitening agent as a safer alternative to hydrogen peroxide-based products and to assess the clinical efficacy of a natural bleaching agent using a self-molding tray system. Methods: In vitro tests were conducted on bovine incisors using water extracts from four seaweeds: Sargassum fulvellum, Saccharina japonica, Gelidium amansii, and Hizikia fusiforme, at a concentration of 250 mg/ml. Tooth color was measured at eight time points using VITA Easyshade V. In parallel, a clinical trial with 35 participants was conducted over three weeks. Subjects used seaweed-based whitening gel with a custom-molded ethylene-vinyl acetate (EVA) tray. The tooth color was confirmed by measuring the maxilla and mandible, and subjective evaluation was also conducted. Results: G. amansii and S. japonica extracts showed significant whitening effects over time, especially in the middle and incisal thirds of teeth. Clinical trial results showed a statistically significant color improvement in all upper and lower anterior teeth, with the most noticeable changes seen in teeth #11 and #41. Participants reported high satisfaction in terms of safety, absence of sensitivity, and visible whitening effects. Approximately 49% noticed whitening within 3 days, and over 90% within 10 days. Conclusions: Seaweed-based whitening agents demonstrated effective and gradual whitening effects, comparable to conventional hydrogen peroxide-based products, but with significantly fewer adverse effects. These natural alternatives offer promising applications for safer, sustained oral care and esthetic improvement, including halitosis reduction and increased salivary secretion.

목차

Ⅰ. 서론

Ⅱ. 연구방법

Ⅲ. 연구결과

Ⅳ. 고찰

Ⅴ. 결론

REFERENCES

키워드

Bovine incisor Clinical trial Seaweed extract Self-molding tray system Tooth whitening effect