Association of dietary inflammatory index with mortality risk: a prospective analysis of the Korea National Health and Nutrition Examination Survey

• 발행기관: 한국역학회
• 저자명: Dahyun Park Hee Ju Jun Garam Jo Soyoung Kwak Min-Jeong Shin
• 간행물 정보: 『Epidemiology and Health』47, 1~12쪽, 전체 12쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2025.01.31

국문 초록

OBJECTIVES: The energy-adjusted dietary inflammatory index (E-DII), a tool developed based on comprehensive research and literature reviews, is used to assess the inflammatory potential of specific diets. Although previous research has demonstrated an association between E-DII and mortality, longitudinal studies investigating a causal relationship in Asian populations are lacking. This study aimed to explore the prospective association between E-DII and the risk of all-cause, cancer, and cardiovascular disease (CVD) mortality using a population-based Korean cohort. METHODS: The analysis included data from 40,596 individuals who participated in the Korea National Health and Nutrition Examination Survey between 2007 and 2015. The exclusion criteria encompassed the diagnosis of cancer or CVD at baseline, pregnancy at baseline, and death within the first 2 years after baseline. The E-DII was calculated using data from 24-hour dietary recall interviews. Cox proportional hazard regression models were employed to calculate hazard ratios (HRs) with 95% confidence intervals (CIs) for mortality risk across E-DII tertiles. RESULTS: Over an 8.2-year follow-up period, 2,070 deaths were recorded. Compared with the lowest E-DII, a higher index was associated with an increased risk of mortality from all causes (HR, 1.45; 95% CI, 1.25 to 1.69), cancer (HR, 1.41; 95% CI, 1.09 to 1.81), and CVD (HR, 1.53; 95% CI, 1.07 to 2.18). The association between E-DII and all-cause mortality was particularly pronounced among individuals with metabolic conditions. CONCLUSIONS: Our findings suggest a strong positive association between high E-DII and increased mortality in Korean adults, especially those with metabolic disorders.

목차

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

NOTES

REFERENCES

키워드

Diet Inflammation Mortality Cardiovascular diseases Cancer

참고문헌

• Oncotarget
• Atherosclerosis
• Arch Gerontol Geriatr
• Lancet
• PLoS One
• Nutr Clin Pract
• Br J Nutr
• Eur J Nutr
• Public Health Nutr
• Br J Nutr
• Public Health Nutr
• Eur J Nutr
• Nutrients
• Br J Nutr
• Nutrients
• Int J Cancer
• Nutrition
• J Epidemiol
• Nutrients
• Adv Nutr
• Clin Nutr
• Nutrients
• Adv Nutr
• J Am Coll Cardiol
• World J Gastroenterol
• Circulation
• Circulation
• Am J Clin Nutr
• Nutrients
• J Clin Oncol
• Cancer J
• Crit Rev Immunol
• Nutrients
• In: Milner JA, Romagnolo DF, editors. Bioactive compounds and cancer
• Epigenomics
• Curr Probl Cardiol
• Front Nutr
• Nutrients
• Nutrients
• Nutrients
• Adv Nutr
• Asia Pac J Clin Nutr
• Adv Nutr
• J Clin Epidemiol