인간과 반려동물에 전파 가능한 해양 유래 자원 분리 장내세균속 그람음성세균의 분포와 특징

• 영문명: Distribution and Characteristics of Gram-negative Enterobacteriaceae Isolated from Marine-derived Resources that Can be Transmitted to Humans and Companion Animals
• 발행기관: 한국동물보건학회
• 저자명: 홍준성(Jun Sung Hong) 배일권(Il Kwon Bae)
• 간행물 정보: 『한국동물보건학회지』4권 2호, 161~171쪽, 전체 11쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2025.06.30

국문 초록

One-Health marine ecosystems are related to humans and animals. In addition, they serve as reservoirs of antibiotic-resistant bacteria and antibiotic resistance genes. However, little is known about the distribution and characteristics of marine-derived bacteria in response to the transmitted factors. The aim of this study was to describe the prevalence and characteristics of Gram-negative bacteria isolated from marine-derived resources that can be transmitted to humans and companion animals. A total of 41 marine-derived resources were collected from 15 regions of nearby oceans in South Korea. Bacterial identification and antimicrobial susceptibility testing were performed by 16S rRNA PCR and sequencing method and disk diffusion method, respectively. The pAmpC genes (CMY-1, CMY-2, DHA, ACC, FOX, and MIR/ACT) were identified through PCR and sequencing. A total of 41 non-duplicated Gram-negative bacteria, comprising 16 different species, were identified. Some isolates showed resistant patterns to ampicillin, amoxicillin, cefoxitin, streptomycin, and ciprofloxacin. 17 isolates carried pAmpC (ACT-6, ACT-15, ACT-20, and MIR-3) in 28 cefoxitin non-susceptible isolates. Our results prescribed that the distribution of marine-derived Gram-negative bacteria and identified the pAmpC producing marine-derived Gram-negative bacteria in South Korea. In this regard, our findings suggest the possibility of transmitting antimicrobial resistance to humans and animals regarding One-Health perspective.

목차

1. 서론

2. 재료 및 방법

3. 결과

4. 고찰

5. 결론

References

키워드

marine humans animals antimicrobial resistance pAmpC