감마선 6 Gy에 조사된 SD Rat에서 홍삼, 삼백초, 복분자 혼합 추출물의 방사선 방호 및 회복 효과

• 영문명: Radiation Protection and Recovery Effects of Red Ginseng, Saururus chinensis (Lour.) Baill. and Rubus coreanus Miq. Mixed Extracts in SD Rat irradiated to Gamma-ray 6 Gy
• 발행기관: 대한방사선과학회(구 대한방사선기술학회)
• 저자명: 진성옥(Seong-Ock Jin) 박재형(Jae-Hyeong Park) 주성현(Sung-Hyun Joo) 최제경(Jae-Gyeong Choi) 민병인(Byung-In Min)
• 간행물 정보: 『방사선기술과학』제47권 제5호, 375~383쪽, 전체 9쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2024.09.30

국문 초록

The purpose of this study is to confirm the radiation protection and recovery effects of natural mixed radiation protection agents. Red Ginseng, Saururus chinensis (Lour.) Baill. and Rubus coreanus Miq. mixed extract was orally ad- ministered to male SD rats and changes were observed in the blood, small intestine and prostate. The experimental group was organized into a general control group (NC Group), mixed extract administration group (RSR Group), 6 Gy irradiation group (IR Group), and irradiation group after administration of the mixed extract (RSR+IR Group). Among them, the RSR Group and RSR+IR Group were orally administered 2 cc (36.6 mg/day/250 g) of the extract once for two weeks at the same time, and at the end of administration, the IR Group and RSR+IR Group were irradiated with 6 Gy whole body radiation. Looking at hematological changes, the RSR + IR Group showed higher recovery and higher levels of white blood cells and platelets than the IR Group. And SOD levels showed high activity in the group administered the extract. Looking at the small intestine, compared to the IR Group, the RSR+IR Group shows better protection and recovery of small intestine villi length. Likewise, in the prostate, there is less cell damage in the RSR+IR Group, and on the 21st day, the prostate spacing is constant, showing a similar pattern to the NC Group. It is believed that the mixed extract used in the study has radiation protection and recovery effects in male SD rats and will be helpful in the study of mixed radiation protection agents.

목차

Ⅰ. 서 론

Ⅱ. 대상 및 방법

Ⅲ. 결 과

Ⅳ. 고 찰

Ｖ. 결 론

REFERENCES

키워드

방사선 혼합 추출물 천연 방사선 방호제 홍삼 삼백초 복분자 Radiation Mixed Extracts Natural Radiation Protection Material Red Ginseng Saururus chinensis (Lour.) Baill. Rubus coreanus Miq.