Long-term treatment of metastatic adenoid cystic carcinoma with sequential brachytherapy and stereotactic body radiotherapy

• 발행기관: 대한방사선종양학회
• 저자명: Allison Y. Zhong Sangwoo S. Kim Austin Hopper Greg White Sayuri Miyauchi Riley N. Jones Dan Scanderbeg Loren K. Mell Elizabeth Weihe Nathalie Boutros Stephen W. Doggett Andrew B. Sharabi
• 간행물 정보: 『대한방사선종양학회지』제42권 제3호, 237~243쪽, 전체 7쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2024.09.30

국문 초록

Adenoid cystic carcinoma (ACC) is a malignancy that is difficult to treat and often metastasizes to the lung. Systemic chemotherapies are not effective for this tumor type, thus local therapies are frequently used. Here, we report a case demonstrating the use of extensive ablative interventions in controlling the progression of metastatic adenoid cystic carcinoma. A patient with ACC developed numerous metastases to his lungs and liver. Local ablative therapies including interstitial brachytherapy and stereotactic body radiotherapy (SBRT) were used to treat approximately 80 different metastases over the course of a decade. Over 850 brachytherapy seeds were implanted in this patient, and the tumor control and patient outcome were good. As of the most recent follow-up in March 2024, the patient has survived for approximately 12 years since his diagnosis of ACC. To our knowledge, this case represents the most brachytherapy treatments reported in a single patient. It highlights the utility of interstitial brachytherapy and SBRT in treating extensive lung and liver metastases.

목차

Introduction

Case Report

Discussion

Statement of Ethics

Conflict of Interest

Funding

Author Contributions

Data Availability Statement

References

키워드

Adenoid cystic carcinoma Brachytherapy Radiation Radiotherapy Neoplasm metastasis