A Randomized Trial Comparing the Effect of Unani Formulation with Metronidazole in Bacterial Vaginosis

• 영문명: A Randomized Trial Comparing the Effect of Unani Formulation with Metronidazole in Bacterial Vaginosis
• 발행기관: 셀메드 세포교정의약학회
• 저자명: Nazia Usmoni Mariyam Roqaiya Mohd Aqil Quadri Arshiya Sultana Taseen Banu Sumbul Alam
• 간행물 정보: 『셀메드』Volume 13 Issue 14, 1~13쪽, 전체 13쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 2023.11.30

국문 초록

Background and objectives: Bacterial vaginosis (BV) is recognized as the most prevalent type of vaginal infection, impacting approximately 19-24% of women in their reproductive years. The recurrence rate of BV is significant, negatively impacting the well-being of affected women. This study aimed to compare the therapeutic effects of a polyherbal Unani formulation and metronidazole in treating bacterial vaginosis. Methodology: In this prospective patient blinded standard controlled trial, a total of 40 individuals with a clinical diagnosis of bacterial vaginosis were randomly assigned to receive either an active control treatment (n = 20) or a test drug (n = 20). In the test drug combination of Acacia catechu, Azadirachta indica and Quercus infectoria in tablet (1g) form in the dose of 2 tablets orally twice daily with water was administered for 3 weeks. In the active control standard drug, metronidazole 400 mg tablet, orally twice daily was given for one week. The primary outcome measure was clinical cure; H. negative Amsel’s criteria and a reduction in subjective symptoms, while the secondary outcome measure was an improvement in SF-36 quality of life (QOL). Results and conclusion: Both the experimental treatment and the metronidazole demonstrated a significant clinical cure for bacterial vaginosis as well as an increase in health-related quality of life. Based on these findings, it appears that the test medication is a potent Unani formulation for the treatment of bacterial vaginosis. A well conducted trial with a bigger sample size is required to corroborate these findings.

목차

INTRODUCTION

Materials and methods

Results and Discussion

Conclusion

References

키워드

bacterial vaginosis polyherbal quality of life Unani medicine