The role of histology on the outcome of sinonasal carcinomas treated with radiotherapy: a single institution experience

• 영문명: The role of histology on the outcome of sinonasal carcinomas treated with radiotherapy: a single institution experience
• 발행기관: 대한방사선종양학회
• 저자명: Ali Kazemian Borna Farazmand Maryam Taherioun Mahdie Razmkhah Mohammad Shirkhoda Amirmohsen Jalaeefar Ata Garajei Mehrdad Jafari Farrokh Heidari Mahdi Aghili Reza Ghalehtaki
• 간행물 정보: 『대한방사선종양학회지』제42권 제2호, 116~123쪽, 전체 8쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2024.06.30

국문 초록

Purpose: Sinonasal malignancies are a rare group of head and neck cancers. We aimed to report the oncological outcomes based on histological types in patients who underwent radiotherapy. Materials and Methods: In this single-institution study, we retrospectively retrieved and analyzed data of patients with sinonasal carcinomas who underwent radiotherapy during 2011-2016 as part of their treatment. The 3-year rate of local, regional, and distant recurrences, and overall survival were evaluated according to the histological type. Results: A total of 28 patients were evaluated in this study, the majority of whom were male (60%). Squamous cell carcinoma (SCC), adenoid cystic carcinoma (ACC), and adenocarcinoma (ADC) were found in 15 patients (53.5%), 8 (28.5%), and 5 (18%), respectively. The highest rates of local and regional recurrences were observed in ACC and SCC, respectively. Distant recurrences were numerically more common in ADC. The 3-year OS was 48%, 50%, and 73% in SCC, ADC, and ACC, respectively. Conclusion: Different histopathologies of sinonasal cancer seem to have different patterns of failure, and this may be considered in the treatment approach.

목차

Introduction

Materials and Methods

Results

Discussion and Conclusion

Statement of Ethics

Conflict of Interest

Acknowledgements

Funding

Author Contributions

Data Availability Statement

References

키워드

Adenoid cystic carcinoma Treatment outcome Squamous cell carcinoma Head and neck neoplasms Radiotherapy Paranasal sinus neoplasms