PET/CT 저선량 적용 시 CT 감쇠보정법에 따른 피폭선량 저감효과

• 영문명: Effect of the Dose Reduction Applied Low Dose for PET/CT According to CT Attenuation Correction Method
• 발행기관: 대한핵의학기술학회
• 저자명: 정승우(Seung Woo Jung) 김홍균(Hong Kyun Kim) 권재범(Jae Beom Kwon) 박성욱(Sung Wook Park) 김명준(Myeong Jun Kim) 신영만(Yeong Man Sin) 김영헌(Yeong Heon Kim)
• 간행물 정보: 『핵의학기술』Vol.18 No.1, 127~133쪽, 전체 7쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2014.05.30

영문 초록

Purpose: Low dose of PET/CT is important because of Patient’s X-ray exposure. The aim of this study was to evaluate the effectiveness of low-dose PET/ CT image through the CTAC and QAC of patient study and phantom study. Materials and Methods: We used the discovery 710 PET/CT (GE). We used the NEMA IEC body phantom for evaluating the PET data corrected by ultra-low dose CT attenuation correction method and NU2-94 phantom for uniformity. After injection of 70.78 MBq and 22.2 MBq of 18 F-FDG were done to each of phantom, PET/CT scans were obtained. PET data were reconstructed by using of CTAC of which dose was for the diagnosis CT and Q. AC of which was only for attenuation correction. Quantitative analysis was performed by use of horizontal profile and vertical profile. Reference data which were corrected by CTAC were compared to PET data which was corrected by the ultra-low dose. The relative error was assessed. Patients with over weighted and normal weight also underwent a PET/CT scans according to low dose protocol and standard dose protocol. Relative error and signal to noise ratio of SUV were analyzed. Results: In the results of phantom test, phantom PET data were corrected by CTAC and Q.AC and they were compared each other. The relative error of Q.AC profile was been calculated, and it was shown in graph. In patient studies, PET data for overweight patient and normal weight patient were reconstructed by CTAC and Q.AC under routine dose and ultra-low dose. When routine dose was used, the relative error was small. When high dose was used, the result of overweight patient was effectively corrected by Q.AC. Conclusion: In phantom study, CTAC method with 80 kVp and 10 mA was resulted in bead hardening artifact. PET data corrected by ultra- low dose CTAC was not quantified, but those by the same dose were quantified properly. In patients’ cases, PET data of over weighted patient could be quantified by Q.AC method. Its relative difference was not significant. Q.AC method was proper attenuation correction method when ultra-low dose was used. As a result, it is expected that Q.AC is a good method in order to reduce patient’s exposure dose.

목차

서론

실험재료 및 방법

결과

고찰 및 결론

요약

REFERENCES

키워드

PET/CT CTAC Q.AC Low dose