SPECT/CT에서 서로 다른 에너지의 방사성동위원소 사용시 영상보정기법의 유용성 평가

• 영문명: The Evaluation of Image Correction Methods for SPECT/CT in Various Radioisotopes with Different Energy Levels
• 발행기관: 대한핵의학기술학회
• 저자명: 신병호(Byung Ho Shin) 김승정(Seung Jeong Kim) 윤석환(Seok Hwan Yun) 김태엽(Tae Yeop Kim) 임정진(Jung Jin Lim) 우재룡(Jae Ryong Woo) 오소원(So Won Oh) 김유경(Yu Kyeong Kim)
• 간행물 정보: 『핵의학기술』Vol.17 No.2, 53~58쪽, 전체 6쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2013.11.30

영문 초록

Purpose: To optimize correction method for SPECT/CT, image quality consisting of resolution and contrast was evaluated using three radioisotopes (⁹⁹ᵐTc, ²⁰¹Tl and ¹³¹I) and three different correction methods; attenuation correction (AC), scatter correction (SC) and both attenuation and scatter correction (ACSC). Materials and Methods: Images were acquired with a SPECT/CT scanner and a conventional CT protocol with an OESM reconstruction algorithm (2 iterations and 10 subsets). For resolution measurement, fixed radioactivity (2.22 kBq) was infused into a spatial resolution phantom and full width at half maximum (FWHM) was measured using a vendor-provided software. For contrast evaluation, radioactive source with a ratio of 1:8 to background was filled in a Flanged Jaszczak phantom and percent contrast (%) were calculated. All the parameters for image quality were compared with non-correction (NC) method. Results: As compared with NC, image resolution of all three isotopes were significantly improved by AC and ACSC, not by SC. In particular, ACSC showed better resolution than AC alone for ⁹⁹ᵐTc and ²⁰¹Tl. Image contrast of all three radioisotopes in a sphere with the largest diameter were enhanced by all correction methods. ACSC showed the highest contrast in all three radioisotopes, which was the most accurate in ⁹⁹ᵐTc (85.9%). Conclusion: Image quality of SPECT/CT was improved in all the radioisotopes by CT-based attenuation correction methods, except SC alone. SC failed to improve resolution in any radioisotopes, but it was effective in contrast enhancement. ACSC would be the best correction method as it improved resolution in radioisotopes with low energy levels and contrast in radioisotope with low energy levels. However, in radioisotope with high energy level, AC would be better than ACSC for resolution improvement.

목차

서론

실험재료 및 방법

결과

고찰 및 결론

요약

REFERENCES

키워드

Attenuation correction Scatter correction Percent contrast FWHM OSEM