Article TOF 기법을 이용한 PET/CT 검사에서 적정 스캔 시간에 대한 정량적 평가

• 영문명: Quantitative Evaluation on Optimal Scan Time of PET/CT Studies Using TOF PET
• 발행기관: 대한핵의학기술학회
• 저자명: 문일상(Il Sang Moon) 이홍재(Hong Jae Lee) 김진의(Jin Eui Kim) 김현주(Hyun Joo Kim)
• 간행물 정보: 『핵의학기술』Vol.16 No.1, 34~37쪽, 전체 4쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2012.04.30

영문 초록

Purpose: To verify the optimal scan time per bed for clinical application, we evaluated the quality of ¹⁸F-FDG images with varying scan times in a phantom and 20 patients with 38 lesions using a Philips (TOF) PET/CT scanner. Materials and Methods: The PET/CT images of a NEMA IEC body phantom and 20 patients (16 males, 4 females) were acquired for 5 different scan times of 20-100 sec per bed with intervals of 20 sec. The activity ratio of hot spheres (diameter of 17 [H1], 22 [H2] and 28 [H3] mm) to the background region in the IEC body phantom was 8-to-1. The contrast recovery coefficient (CRC) and standard uptake value (SUV) based on ROIs of hot spheres and background region were calculated. The noise in each background region was estimated as the ratio of SD of counts to the mean counts in the background region. On the patient image, the injected dose of ¹⁸F-FDG was 444±74 MBq and the SUVs in the 38 hot lesions were measured. Results: The two scan time groups (LT-60 [<60 sec] and GT-60 [≥60 sec]) were compared. In the phantom study, the coefficient of deviations (CVs, %) of CRC and SUV in LT-60 (H1: 14.2 and 7.3, H2: 11.4 and 7.8, H3: 4.9 and 3.2) were higher than GT-60 (H1: 8.9 and 2.8, H1: 8.2 and 5.0, H3: 2.0 and 1.6). In the patient study, the mean CV of CRC and SUV in LT-60 (4.0) was higher than GT-60 (1.2). Conclusion: This study showed that noise increased as the scan time decreased. High noise for the scan time <60 sec per bed yielded high variation of SUV and CRC. Therefore, considering PET/CT image quality, the scan time per bed in the TOF PET/CT scanner should be at least ≥60 sec.

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실험 재료 및 방법

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SUV CRC scan time LT-60 GT-60