PET/CT 3D 영상에서 감쇠보정 위치 변화 방법을 이용한 영상 재구성법의 평가

• 영문명: The Evaluation of Reconstruction Method Using Attenuation Correction Position Shifting in 3D PET/CT
• 발행기관: 대한핵의학기술학회
• 저자명: 홍건철(Gun Chul Hong) 박선명(Sun Myung Park) 정은경(Eun Kyung Jung) 최춘기(Choon Ki Choi) 석재동(Jae Dong Seok)
• 간행물 정보: 『핵의학기술』Vol.14 No.2, 172~176쪽, 전체 5쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2010.10.30

영문 초록

Purpose: The patients’ moves occurred at PET/CT scan will cause the decline of correctness in results by resulting in inconsistency of Attenuation Correction (AC) and effecting on quantitative evaluation. This study has evaluated the utility of reconstruction method using AC position changing method when having inconsistency of AC depending on the position change of emission scan after transmission scan in obtaining PET/CT 3D image. Materials and Methods: We created 1 mL syringe injection space up to ±2, 6, 10 cm toward x and y axis based on central point of polystyrene (20×20110 cm) into GE Discovery STE16 equipment. After projection of syringe with ¹⁸F-FDG 5 k㏃/mL, made an emission by changing the position and obtained the image by using AC depending on the position change. Reconstruction method is an iteration reconstruction method and is applied two times of iteration and 20 of subset, and for every emission data, decay correction depending on time pass is applied. Also, after setting ROI to the position of syringe, compared %Difference (%D) at each position to radioactivity concentrations (k㏃/mL) and central point. Results: Radioactivity concentrations of central point of emission scan is 2.30 k㏃/mL and is indicated as 1.95, 1.82 and 1.75 k㏃/mL, relatively for +x axis, as 2.07, 1.75 and 1.65 k㏃/mL for -x axis, as 2.07, 1.87 and 1.90 k㏃/mL for +y axis and as 2.17, 1.85 and 1.67 k㏃/mL for -y axis. Also, %D is yield as 15, 20, 23% for +x axis, as 9, 23, 28% for -x axis, as 12, 21, 20% for +y axis and as 8, 22, 29% for -y axis. When using AC position changing method, it is indicated as 2.00, 1.95 and 1.80 k㏃/mL, relatively for +x axis, as 2.25, 2.15 and 1.90 k㏃/mL for -x axis, as 2.07, 1.90 and 1.90 k㏃/mL for +y axis, and as 2.10, 2.02, and 1.72 k㏃/mL for -y axis. Also, %D is yield as 13, 15, 21% for +x axis, as 2, 6, 17% for -x axis, as 9, 17, 17% for +y axis, and as 8, 12, 25% for -y axis. Conclusion: When in inconsistency of AC, radioactivity concentrations for using AC position changing method increased average of 0.14, 0.03 k㏃/mL at x, y axis and %D was improved 6.1, 4.2%. Also, it is indicated that the more far from the central point and the further position from the central point under the features that spatial resolution is lowered, the higher in lowering of radioactivity concentrations. However, since in actual clinic, attenuation degree increases more, it is considered that when in inconsistency, such tolerance will be increased. Therefore, at the lesion of the part where AC is not inconsistent, the tolerance of radioactivity concentrations will be reduced by applying AC position changing method.

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실험재료 및 방법

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키워드

Attenuation correction reconstruction radio activity concentrations %Difference