전신 뼈 검사에서 Wide Beam Reconstruction 기법의 유용성

• 영문명: Utility of Wide Beam Reconstruction in Whole Body Bone Scan
• 발행기관: 대한핵의학기술학회
• 저자명: 김정열(Jung Yul Kim) 강청구(Chung Koo Kang) 박민수(Hoon Hee Park) 박훈희(Min Soo Park) 임한상(Han Sang Lim) 김재삼(Jae Sam Kim) 이창호(Chang Ho Lee)
• 간행물 정보: 『핵의학기술』Vol.14 No.1, 83~89쪽, 전체 7쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2010.06.30

영문 초록

Department of Nuclear Medicine, Severance hospital, Yonsei University Health System, Korea Purpose: The Wide Beam Reconstruction (WBR) algorithms that UltraSPECT, Ltd. (U.S) has provides solutions which improved image resolution by eliminating the effect of the line spread function by collimator and suppression of the noise. It controls the resolution and noise level automatically and yields unsurpassed image quality. The aim of this study is WBR of whole body bone scan in usefulness of clinical application. Materials and Methods: The standard line source and single photon emission computed tomography (SPECT) reconstructed spatial resolution measurements were performed on an INFINA (GE, Milwaukee, WI) gamma camera, equipped with low energy high resolution (LEHR) collimators. The total counts of line source measurements with 200 kcps and 300 kcps. The SPECT phantoms analyzed spatial resolution by the changing matrix size. Also a clinical evaluation study was performed with forty three patients, referred for bone scans. First group altered scan speed with 20 and 30 cm/min and dosage of 740 MBq (20 mCi) of ⁹⁹ᵐTc-HDP administered but second group altered dosage of ⁹⁹ᵐTc-HDP with 740 and 1,110 MBq (20 mCi and 30 mCi) in same scan speed. The acquired data was reconstructed using the typical clinical protocol in use and the WBR protocol. The patient’s information was removed and a blind reading was done on each reconstruction method. For each reading, a questionnaire was completed in which the reader was asked to evaluate, on a scale of 1-5 point. Results: The result of planar WBR data improved resolution more than 10%. The Full-Width at Half-Maximum (FWHM) of WBR data improved about 16% (Standard: 8.45, WBR: 7.09). SPECT WBR data improved resolution more than about 50% and evaluate FWHM of WBR data (Standard: 3.52, WBR: 1.65). A clinical evaluation study, there was no statistically significant difference between the two method, which includes improvement of the bone to soft tissue ratio and the image resolution (first group p=0.07, second group p=0.458). Conclusion: The WBR method allows to shorten the acquisition time of bone scans while simultaneously providing improved image quality and to reduce the dosage of radiopharmaceuticals reducing radiation dose. Therefore, the WBR method can be applied to a wide range of clinical applications to provide clinical values as well as image quality.

목차

서론

실험재료 및 방법

결과

고찰 및 결론

요약

REFERENCES

키워드

Wide Beam Reconstruction (WBR) Xpress.BoneTM Whole body bone scan