골절의 절대위험도 평가방법에서 GE Prodigy와 FRAX Tool의 비교분석에 관한 고찰

• 영문명: Studies on the Comparative Analysis Between GE Prodigy and FRAXTM Tool in Absolute Fracture Risk Assessment Tool
• 발행기관: 대한핵의학기술학회
• 저자명: 이화진(Hwa Jin Lee) 이효영(Hyo Yeong Lee) 윤종준(Jong Jun Yun) 이무석(Mu Seok Lee) 송현석(Hyeon Seok Song) 박세윤(Se Yun Park) 정지욱(Ji Uk Jeong)
• 간행물 정보: 『핵의학기술』Vol.13 No.2, 137~142쪽, 전체 6쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2009.10.30

영문 초록

Purpose: World Health Organization (WHO) have suggested that an individual’s 10-year absolute fracture risk is more reliable than Bone Mineral Density (BMD) measurement as the predictor of osteoporotic fracture. In 2008, Fracture Risk Assessment Tool (FRAXTM) was developed by WHO to evaluate fracture risk of patients based on individual’s clinical risk factors. The purpose of this study is to offer the comparative analysis of the existing GE prodigy and FRAXTM Tool in Absolute Fracture Risk Assessment Tool. Materials and Methods: 201 women (55±3.5 years) underwent femoral neck BMD measurement using GE Prodigy. The 10-year probability (%) of hip fracture (or a major osteoporosis-related fracture) was estimated using T-scores of GE prodigy and FRAXTM. We made a comparative analysis of these data using SPSS (Ver.12). Results: There was a significant difference statistically between T-score (-0.52±0.97) of GE prodigy and T-score (-1.45±0.81) of FRAXTM (r=0.977, p=0.000). Also, there was a significant difference statistically between a major osteoporosis- related fracture (9.15±3.71) of GE prodigy and a major osteoporosis-related fracture (4.87±1.51) of FRAXTM (r=0.909, p=0.000). Moreover, a statistically significant difference was found in the 10-year probability of hip fracture of GE prodigy (1.56±1.48) and of hip fracture (0.53±0.61) of FRAXTM (r=0.905, p=0.000). Conclusions: There was a significant difference statistically between GE prodigy and FRAXTM Tool in Absolute Fracture Risk Assessment Tool. Especially, T-score, a major osteoporosis-related fracture and the 10-year probability of hip fracture that were estimated using GE prodigy tended to show the higher results than one evaluated by FRAXTM Tool. In conclusion, FRAXTM Tool may provide a better tool. The application of FRAXTM Tool as a fracture predictor remains to be clarified.

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실험재료 및 방법

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키워드

Fracture risk FRAX GE Prodigy WHO