Cr-51 EDTA GFR 검사 결과의 분석 및 의의

• 영문명: Estimation of Glomerular Filtration Rate using Chromium-51 EDTA
• 발행기관: 대한핵의학기술학회
• 저자명: 임수연(Soo Yeon Lim) 문형호(Hyoung Ho Moon) 유선희(Seon Hee Yoo) 조시만(Shee Man Cho)
• 간행물 정보: 『핵의학기술』Vol.13 No.1, 98~103쪽, 전체 6쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2009.05.30

영문 초록

Purpose: Correct estimation of Glomerular filtration rate (GFR) is very important for an accurate clinical assessment of the kidney function. This study compares four GFR markers, a serum creatinine-based estimation using MDRD formula, Cystatin-C, Cr-51 EDTA 2 samples and 6 samples. Materials and Methods: Serum creatinine concentrations, Cystatin-C serum concentrations and Cr-51 EDTA clearance are measured in 43 patients who received or donated kidney. Results: The correlation coefficient between serum based estimated GFR (MDRD) and Cr-51 EDTA 6 samples was 0.817 (p<0.01). The correlation coefficient between Cystatin-C based GFR and EDTA 6 samples was 0.7322 (p<0.01). Regression analysis showed a statistically significant correlation between Cr-51 EDTA 2 samples and 6 samples (r=0.971, p<0.01). Mean value and ±2SD for the difference between Cr-51 EDTA 2 samples and 6 samples were 4.7 mL/min and ±9.3 respectively. Conclusions: The estimation of two samples Cr-51 EDTA showed that the method can be simplified by reducing blood samples without losing its high accuracy.

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실험재료 및 방법

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키워드

Glomerular filtration rate Cr-51 EDTA Estimated GFR Cystatin-C